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Scholar Results 1 - 10 of 12 citing De Cosmo: PC-1 amino acid variant Q121 is associated with a lower glomerular filtration rate.... (0.11 sec) 

Histopathology of diabetic nephropathy

- nih.gov
P Fioretto, M Mauer - Seminars in nephrology, 2007 - Elsevier
The clinical manifestations of diabetic nephropathy, proteinuria, increased blood pressure, and
decreased glomerular filtration rate, are similar in type 1 and type 2 diabetes; however, the renal
lesions underlying renal dysfunction in the 2 conditions may differ. Indeed, although ...
Cited by 21 - Related articles - All 9 versions

The Q121/Q121 Genotype of ENPP1/PC-1 Is Associated with Lower BMI in Non- …


S Prudente, M Chandalia, E Morini, R Baratta, B … - 2007 - nature.com
* The costs of publication of this article were defrayed, in part, by the payment of page
charges. This article must, therefore, be hereby marked "advertisement" in accordance with 18
USC Section 1734 solely to indicate this fact. ... Received 2 May 2006; Revised 00; ...
Cited by 13 - Related articles - All 3 versions

Mechanisms of Disease: ectonucleotide pyrophosphatase phosphodiesterase 1 as …


N Abate, M Chandalia, R Di Paola, DW Foster, … - Nature Reviews …, 2006 - nature.com
Insulin resistance is pathogenic for type 2 diabetes and cardiovascular disease. Several inhibitors
of insulin signaling have a role in human insulin resistance. The transmembrane glycoprotein
ectonucleotide pyrophosphatase phosphodiesterase 1 (E-NPP1; also known as plasma ...
Cited by 11 - Related articles - BL Direct - All 3 versions

ENPP1 gene, insulin resistance and related clinical outcomes


S Bacci, S De Cosmo, S Prudente, V … - Current Opinion in Clinical …, 2007 - journals.lww.com
Purpose of review: Insulin resistance plays a significant role in both morbidity and mortality of
the general population. Understanding the molecular mechanisms of insulin resistance would
help the identification of at-risk individuals in the presymptomatic stage, and the discovery ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Genome scan for determinants of serum uric acid variability

- asnjournals.org
SD Nath, VS Voruganti, NH Arar, F Thameem, … - Journal of the American …, 2007 - Am Soc Nephrol
Elevated serum uric acid level is associated with obesity, insulin resistance, diabetes,
nephropathy, and hypertension. Epidemiologic studies suggest that serum uric acid levels are
heritable. We sought to identify chromosomal regions harboring quantitative trait loci that ...
Cited by 8 - Related articles - All 4 versions

The vascular ectonucleotidase ENTPD1 is a novel renoprotective factor in diabetic …

- shouxi.net
DJ Friedman, HG Rennke, E Csizmadia, K Enjyoji, SC … - Diabetes, 2007 - Am Diabetes Assoc
Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) (also known as CD39) is the
dominant vascular ectonucleotidase. By hydrolyzing ATP and ADP to AMP, ENTPD1 regulates
ligand availability to a large family of P2 (purinergic) receptors. Modulation of extracellular ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Ectonucleotidases in the kidney


DG Shirley, RM Vekaria, J Sévigny - Purinergic Signalling - Springer
Abstract Members of all four families of ectonucleoti- dases, namely ectonucleoside triphosphate
diphosphohy- drolases (NTPDases), ectonucleotide pyrophosphatase/ phosphodiesterases
(NPPs), ecto-5′-nucleotidase and alka- line phosphatases, have been identified in the ...
Cited by 5 - Related articles - All 2 versions

Lack of evidence for the 1484insG variant at the 3'-UTR of the protein tyrosine …

- oxfordjournals.org
S De Cosmo, A Marucci, E Ciociola, R Di Paola, L … - Nephrology Dialysis …, 2004 - ERA-EDTA
Insulin resistance (IR) is likely to precede and to play a role in diabetic nephropathy (DN) in both
type 1 (T1D) [1] and type 2 diabetes [2]. IR and DN may also share common genetic determinants
[3–6]. The gene encoding PTP1B, a tyrosine phosphatase which inhibits insulin ...
Related articles - BL Direct - All 4 versions

PC-1 及其基因多态性与胰岛素抵抗和心血管疾病的关系


何丽娜, 王梦洪 - 实用临床医学 (江西), 2005 - cqvip.com
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维普资讯 中文期刊·专业文章. 维普专业检索Google学术. 临床医学 >> 实用临床医学(江西) >>
2005年6卷9期 >> 摘要. PC-1及其基因多态性与胰岛素抵抗和心血管疾病的关系. 评论推荐. 下载全文 ...
Related articles - All 4 versions

[PDF] ASPECTS RÉCENTS DES LÉSIONS RÉNALES DU DIABÈTE


HDELAN DIABÉTIQUE - soc-nephrologie.org
Dans le diabète de type 1, les lésions rénales touchent à la fois les glomérules, les
artérioles, l'interstitium et les tubes [1-5], mais l'atteinte glomérulaire est la lésion la plus
importante. Elle est caractérisée par un épaississement des membra- nes basales ...
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