- ►ahajournals.org P Dandona, A Aljada, A Chaudhuri, P … - Circulation, 2005 - Am Heart Assoc The original description of the metabolic syndrome by Reaven 1 consisted of
obesity, insulin resistance, hypertension, impaired glucose tolerance or
diabetes, hyperinsulinemia and dyslipidemia characterized by elevated ... Cited by 385 - Related articles - All 7 versions
- ►nih.gov L Langouche, I Vanhorebeek, D Vlasselaers, … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig The vascular endothelium controls vasomotor tone and microvascular flow and
regulates trafficking of nutrients and biologically active molecules. When
endothelial activation is excessive, compromised microcirculation and ... Cited by 314 - Related articles - BL Direct - All 11 versions
- ►diabetesjournals.org FB Stentz, GE Umpierrez, R Cuervo, AE … - Diabetes, 2004 - Am Diabetes Assoc Acute and chronic hyperglycemia are proinflammatory states, but the status of
proinflammatory cytokines and markers of oxidative stress and cardiovascular
risks is not known in hyperglycemic crises of diabetic ketoacidosis (DKA) ... Cited by 131 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org R Garg, A Chaudhuri, F Munschauer, P … - Stroke, 2006 - Am Heart Assoc Summary of Review— Hyperglycemia induces a pro-oxidative and proinflammatory
state that can cause direct neuronal toxicity. Hyperglycemia-mediated increase
in matrix metalloproteinase-9 can cause neuronal damage by an increase in ... Cited by 94 - Related articles - All 6 versions
- ►ajcn.org A Aljada, H Ghanim, P Mohanty, T Syed, A … - American journal of clinical nutrition, 2004 - Am Soc Nutrition Background: Glucose intake has been shown to cause an increase in intranuclear
nuclear factor- B and a decrease in inhibitor B that are consistent with a
proinflammatory effect. We investigated the effect of glucose intake on 2 ... Cited by 83 - Related articles - BL Direct - All 7 versions
P Dandona, A Aljada, A Chaudhuri, P … - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer The endothelium of blood vessels not only provides a mechanical lining, it is a
biologically active inner layer of the blood vessel which serves several
important func- tions. It ensures the patency of the blood vessel so that ... Cited by 42 - Related articles - BL Direct - All 3 versions
- ►nutrition.org KH Treiber, DS Kronfeld, RJ Geor - Journal of Nutrition, 2006 - Am Soc Nutrition Insulin is a major regulatory hormone in glucose and fat metabolism, vascular
function, inflammation, tissue remodeling, and the somatotropic axis of growth.
Insulin resistance alters insulin signaling by decreasing insulin action in ... Cited by 37 - Related articles - All 4 versions
- ►endojournals.org A Viardot, ST Grey, F Mackay, D Chisholm - Endocrinology, 2007 - Endocrine Soc Hyperglycemia in critical illness is a common complication and a strong
independent risk factor for morbidity and death. Intensive insulin therapy
decreases this risk by up to 50%. It is unclear to what extent this benefit ... Cited by 30 - Related articles - BL Direct - All 4 versions
NP Kadoglou, SS Daskalopoulou, D Perrea, … - Angiology, 2005 - ang.sagepub.com Diabetes mellitus (DM) is associated with an increased incidence of
cardiovascular events and microvascular complications. These complications
contribute to the morbidity and mortality associated with DM. There is ... Cited by 31 - Related articles - All 3 versions
P Dandona, A Chaudhuri, H Ghanim, P … - The American Journal of Cardiology, 2007 - Elsevier Previously published data demonstrate clearly that hyperglycemia worsens
morbidity and mortality in patients in intensive care, those with acute
myocardial infarction and stroke, and those who undergo coronary artery ... Cited by 29 - Related articles - All 16 versions
