ME Trujillo, PE Scherer - Journal of internal medicine, 2005 - edulife.com.br Adiponectin is an adipocyte-derived hormone that was discovered in 1995. Unlike
leptin, which was identified around the same time, the clinical rele- vance of
adiponectin remained obscure for a number of years. However, starting in ... Cited by 291 - Related articles - View as HTML - All 5 versions
- ►diabetesjournals.org C Lara-Castro, N Luo, P Wallace, RL Klein, … - Diabetes, 2006 - Am Diabetes Assoc Adiponectin circulates in human plasma mainly as a 180-kDa low molecular weight
(LMW) hexamer and a high molecular weight (HMW) multimer of ∼360 kDa. We
comprehensively examined the relationships between circulating levels of ... Cited by 177 - Related articles - BL Direct - All 5 versions
- ►endojournals.org ME Trujillo, PE Scherer - Endocrine reviews, 2006 - Endocrine Soc The endocrine functions of the adipose organ are widely studied at this stage.
The adipose organ, and in particular adipocytes, communicate with almost all
other organs. Although some adipose tissue pads assume the functions as ... Cited by 115 - Related articles - BL Direct - All 9 versions
- ►eje.org C Pagano, G Soardo, W Esposito, F Fallo, L … - European Journal of Endocrinology, 2005 - eje.org Objectives: Nonalcoholic fatty liver disease (NAFLD) is a major cause of
liver-related morbidity and is frequently associated with obesity and metabolic
syndrome. The recently discovered hormone adiponectin is produced by ... Cited by 97 - Related articles - All 7 versions
Y Matsuzawa - Atherosclerosis (Supplements)(Component), 2005 - Elsevier Adiponectin is the most abundant adipose-specific protein. Its expression is
reduced in obesity, insulin resistance and type 2 diabetes, and plasma
concentrations are inversely related to body weight, especially visceral ... Cited by 82 - Related articles - All 11 versions
- ►shouxi.net IM Heid, SA Wagner, H Gohlke, B Iglseder, JC … - Diabetes, 2006 - Am Diabetes Assoc The associations of the adiponectin (APM1) gene with parameters of the metabolic
syndrome are inconsistent. We performed a systematic investigation based on
fine-mapped single nucleotide polymorphisms (SNPs) highlighting the genetic ... Cited by 52 - Related articles - BL Direct - All 6 versions
PM Catalano, M Hoegh, J Minium, L Huston- … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: Adiponectin is upregulated during adipogenesis and
downregulated in insulin-resistant states. The mechanism(s) governing the
re-arrangements from adipogenesis to facilitated lipolysis during pregnancy ... Cited by 53 - Related articles - BL Direct - All 4 versions
- ►physoc.org R Wolk, VK Somers - Experimental Physiology, 2007 - Physiological Soc The metabolic syndrome represents a clustering of several interrelated risk
factors of metabolic origin that are thought to increase cardiovascular risk. It
is still uncertain whether this clustering results from multiple underlying ... Cited by 47 - Related articles - BL Direct - All 13 versions
M Nishida, T Funahashi, I Shimomura - Medical Molecular Morphology, 2007 - Springer Abstract Adipose tissue, which classically has been consid- ered as an
energy-storing organ, is now viewed as a massive source of bioactive substances
such as leptin, tumor necrosis factor (TNF)-α, and adiponectin. ... Cited by 41 - Related articles - BL Direct - All 3 versions
M Krebs, M Roden - Diabetes Obesity and Metabolism, 2005 - pt.wkhealth.com Increased body fat content correlates with insulin resistance and is a key
feature of type 2 diabetes. Excessive intake of fat results in deposition of
lipids not only in fat tissue but also in skeletal muscle and liver. ... Cited by 39 - Related articles - BL Direct - All 6 versions
