G Soltesz - Diabetologia, 2003 - Springer The spectrum of diabetes in the young has widened; it now includes monogenic
diseases, for example the various forms of permanent and transient neonatal di-
abetes and MODY as well as the emerging obesity- associated Type 2 diabetes ... Cited by 48 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] M Shepherd, ER Pearson, J Houghton, G Salt, … - Diabetes Care, 2003 - Am Diabetes Assoc Type 1 diabetes is associated with other autoimmune diseases. Many diabetes
centers routinely screen patients with type 1 diabetes for auto- immune thyroid
disease (ATD). The pres- ence of two autoimmune diseases raises the ... Cited by 35 - Related articles - BL Direct - All 5 versions
S Ellard, K Colclough - Human mutation, 2006 - interscience.wiley.com Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes
mellitus characterized by autosomal dominant inheritance, early age of onset
(often <25 years of age), and pancreatic -cell dysfunction. MODY is both ... Cited by 32 - Related articles - BL Direct - All 4 versions
FMA Giuffrida, AF Reis - Diabetes Obesity and Metabolism, 2005 - interscience.wiley.com Genetic factors play an important role in various forms of diabetes mellitus
(DM), but inheritance is complex and interacts with environmental factors.
Although in most cases type 2 DM (T2DM) and T1DM are polygenic disorders, ... Cited by 32 - Related articles - All 4 versions
- ►diabetesjournals.org EL Edghill, AL Gloyn, KM Gillespie, AP … - Diabetes, 2004 - Am Diabetes Assoc We have recently shown that permanent neonatal diabetes can be caused by
activating mutations in KCNJ11 that encode the Kir6.2 subunit of the ß-cell
ATP-sensitive K + channel. Some of these patients were diagnosed after 3 ... Cited by 25 - Related articles - BL Direct - All 4 versions
M Shepherd, AT Hattersley - Clinical Medicine, Journal of the Royal College of …, 2004 - ingentaconnect.com ABSTRACT – Hepatocyte nuclear factor-1 a (HNF-1 a ) maturity onset diabetes of
the young (MODY) is the commonest cause of monogenic diabetes but is frequently
misdiagnosed as type 1 diabetes. The availability of genetic testing in ... Cited by 24 - Related articles - BL Direct - All 3 versions
UK Exeter, PS Klingensmith - Pediatric diabetes, 2006 - dr-agha.com Authors: Andrew Hattersley, Institute of Biomedical and Clinical Sciences,
Peninsula Medical School, Exeter, UK Jan Bruining, Sophia Children's Hospital,
Rotterdam, the Netherlands Julian Shield, Department of Child Health, ... Cited by 20 - Related articles - View as HTML - BL Direct - All 6 versions
- ►nih.gov AS Slingerland - Reviews in Endocrine & Metabolic Disorders, 2006 - Springer Abstract Monogenic diabetes results from one or more mutations in a single gene
which might hence be rare but has great impact leading to diabetes at a very
young age. It has resulted in great challenges for researchers elucidating ... Cited by 12 - Related articles - BL Direct - All 6 versions
- ►oxfordjournals.org P Narendran, E Estella, S Fourlanos - Qjm, 2005 - Oxford Univ Press There are over one million islets in a healthy adult pancreas. They make up 1%
of the total pancreatic volume, weigh about 1 g, and contain about 1 mg of
insulin. 4 Histological analysis of the pancreas from patients with type 1 ... Cited by 7 - Related articles - BL Direct - All 7 versions
M Shepherd - Practical Diabetes International, 2003 - interscience.wiley.com Maturity onset diabetes of the young (MODY) accounts for 1% of diabetes in the
UK but the young age of diagnosis, high glucose values in slim patients and lack
of professionals' familiarity with the family history often lead to a ... Cited by 2 - Related articles - BL Direct
