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Scholar Results 1 - 10 of about 44 citing Kubaszek: The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but.... (0.10 sec) 

ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes


N Abate, M Chandalia, P Satija, B Adams- … - Diabetes, 2005 - Am Diabetes Assoc
Genetic susceptibility modulates the impact of obesity on risk for type 2
diabetes. The present study evaluates the role of ENPP1 K121Q polymorphism in
prediction of type 2 diabetes in three populations that differ in ...
Cited by 74 - Related articles - All 9 versions

Candidate genes for type 2 diabetes


H Parikh, L Groop - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer
About 150 million people suffer from type 2 diabetes in the world today and it
has been predicted that this num- ber will be doubled within 15 years [1]. It is
no longer a disease of the elderly, age at onset has decreased with the ...
Cited by 61 - Related articles - BL Direct - All 3 versions

Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance

- endojournals.org
N Abate, L Carulli, A Cabo-Chan Jr, M … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
Genetic susceptibility may be responsible for high prevalence of insulin
resistance in Asian Indians. This study was carried out in samples of local
Asian Indians and Caucasians to determine whether plasma cell membrane ...
Cited by 61 - Related articles - BL Direct - All 4 versions

Genetic markers: progress and potential for cardiovascular disease


GH Gibbons, CC Liew, MO Goodarzi, JI Rotter … - Circulation, 2004 - Am Heart Assoc
From the Cardiovascular Research Institute (GHG), Morehouse School of Medicine,
Atlanta, Ga; the Department of Medicine (CCL, RP, VJD), Brigham and Women's
Hospital, Boston, Mass; Medical Genetics Institute (MOG, JIR), Departments ...
Cited by 57 - Related articles - BL Direct - All 7 versions

The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/ …


S Bacci, O Ludovico, S Prudente, YY Zhang, R … - Diabetes, 2005 - Am Diabetes Assoc
Insulin resistance (IR) is pathogenic for type 2 diabetes and coronary artery
disease (CAD). The K121Q polymorphism of the ENPP1/PC-1 gene is associated with
IR. Our aim was to investigate the role of the 121Q variant on the risk of ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, …

- pubget.com [PDF] 
N Grarup, SA Urhammer, J Ek, A Albrechtsen, … - Diabetologia, 2006 - Springer
Page 1. ARTICLE Studies of the relationship between the ENPP1 K121Q polymorphism
and type 2 diabetes, insulin resistance and obesity ...
Cited by 41 - Related articles - BL Direct - All 5 versions

Association of K121Q polymorphism in ENPP1 (PC-1) with BMI in Caucasian and African- …


N Matsuoka, A Patki, HK Tiwari, DB Allison, … - International Journal of Obesity, 2005 - nature.com
To test for association of the ectonucleotide pyrophosphatase/phosphodiesterase
1 (ENPP1) K121Q polymorphism with body mass index (BMI) and diabetes in a large
sample of Caucasians and African-Americans by selectively genotyping ...
Cited by 40 - Related articles - BL Direct - All 4 versions

New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes …

- diabetesjournals.org
J Bochenski, G Placha, K Wanic, M Malecki, J … - Diabetes, 2006 - Am Diabetes Assoc
The K121Q polymorphism in ectonucleotide pyrophosphatase/phosphodiesterase 1
(ENPP1) is associated with type 2 diabetes and obesity. The possibility of other
ENPP1 polymorphisms influencing these phenotypes has received little ...
Cited by 34 - Related articles - BL Direct - All 6 versions

Gene variants, insulin resistance, and dyslipidaemia


M Laakso - Current opinion in lipidology, 2004 - journals.lww.com
Recent findings: Common polymorphisms in the PC-1, insulin receptor substrate 1
and 2, and PPAR-γ2 genes have been linked to insulin resistance and
dyslipidaemia, although the results have not been consistent. However, the ...
Cited by 30 - Related articles - BL Direct - All 6 versions

No evidence for association of the ENPP1 (PC-1) K121Q variant with risk of type 2 diabetes …

- tokushima-u.ac.jp [PDF] 
P Keshavarz, H Inoue, Y Sakamoto, K Kunika, … - Journal of Human Genetics, 2006 - Springer
Abstract Ecto-nucleotide pyrophosphatase/phosphodi- esterase 1 (ENPP1, also
known as PC-1) inhibits insulin signal transduction pathway(s). Previous studies
have demonstrated the K121Q variant of the ENPP1 gene to have a significant ...
Cited by 29 - Related articles - BL Direct - All 9 versions


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