N Abate, M Chandalia, P Satija, B Adams- … - Diabetes, 2005 - Am Diabetes Assoc Genetic susceptibility modulates the impact of obesity on risk for type 2
diabetes. The present study evaluates the role of ENPP1 K121Q polymorphism in
prediction of type 2 diabetes in three populations that differ in ... Cited by 74 - Related articles - All 9 versions
H Parikh, L Groop - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer About 150 million people suffer from type 2 diabetes in the world today and it
has been predicted that this num- ber will be doubled within 15 years [1]. It is
no longer a disease of the elderly, age at onset has decreased with the ... Cited by 61 - Related articles - BL Direct - All 3 versions
- ►endojournals.org N Abate, L Carulli, A Cabo-Chan Jr, M … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc Genetic susceptibility may be responsible for high prevalence of insulin
resistance in Asian Indians. This study was carried out in samples of local
Asian Indians and Caucasians to determine whether plasma cell membrane ... Cited by 61 - Related articles - BL Direct - All 4 versions
GH Gibbons, CC Liew, MO Goodarzi, JI Rotter … - Circulation, 2004 - Am Heart Assoc From the Cardiovascular Research Institute (GHG), Morehouse School of Medicine,
Atlanta, Ga; the Department of Medicine (CCL, RP, VJD), Brigham and Women's
Hospital, Boston, Mass; Medical Genetics Institute (MOG, JIR), Departments ... Cited by 57 - Related articles - BL Direct - All 7 versions
S Bacci, O Ludovico, S Prudente, YY Zhang, R … - Diabetes, 2005 - Am Diabetes Assoc Insulin resistance (IR) is pathogenic for type 2 diabetes and coronary artery
disease (CAD). The K121Q polymorphism of the ENPP1/PC-1 gene is associated with
IR. Our aim was to investigate the role of the 121Q variant on the risk of ... Cited by 54 - Related articles - BL Direct - All 5 versions
- ►pubget.com [PDF] N Grarup, SA Urhammer, J Ek, A Albrechtsen, … - Diabetologia, 2006 - Springer Page 1. ARTICLE Studies of the relationship between the ENPP1 K121Q polymorphism
and type 2 diabetes, insulin resistance and obesity ... Cited by 41 - Related articles - BL Direct - All 5 versions
N Matsuoka, A Patki, HK Tiwari, DB Allison, … - International Journal of Obesity, 2005 - nature.com To test for association of the ectonucleotide pyrophosphatase/phosphodiesterase
1 (ENPP1) K121Q polymorphism with body mass index (BMI) and diabetes in a large
sample of Caucasians and African-Americans by selectively genotyping ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org J Bochenski, G Placha, K Wanic, M Malecki, J … - Diabetes, 2006 - Am Diabetes Assoc The K121Q polymorphism in ectonucleotide pyrophosphatase/phosphodiesterase 1
(ENPP1) is associated with type 2 diabetes and obesity. The possibility of other
ENPP1 polymorphisms influencing these phenotypes has received little ... Cited by 34 - Related articles - BL Direct - All 6 versions
M Laakso - Current opinion in lipidology, 2004 - journals.lww.com Recent findings: Common polymorphisms in the PC-1, insulin receptor substrate 1
and 2, and PPAR-γ2 genes have been linked to insulin resistance and
dyslipidaemia, although the results have not been consistent. However, the ... Cited by 30 - Related articles - BL Direct - All 6 versions
- ►tokushima-u.ac.jp [PDF] P Keshavarz, H Inoue, Y Sakamoto, K Kunika, … - Journal of Human Genetics, 2006 - Springer Abstract Ecto-nucleotide pyrophosphatase/phosphodi- esterase 1 (ENPP1, also
known as PC-1) inhibits insulin signal transduction pathway(s). Previous studies
have demonstrated the K121Q variant of the ENPP1 gene to have a significant ... Cited by 29 - Related articles - BL Direct - All 9 versions