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Scholar Results 1 - 10 of about 113 citing Steffes: β-Cell function and the development of diabetes-related complications in the Diabetes.... (0.10 sec) 

Autologous nonmyeloablative hematopoietic stem cell transplantation in newly …

- sbhh.com.br [PDF] 
JC Voltarelli, CEB Couri, ABPL Stracieri, MC Oliveira, … - Jama, 2007 - Am Med Assoc
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Cited by 135 - Related articles - BL Direct - All 19 versions

Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus

- nih.gov
KI Rother, DM Harlan - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig
Worldwide, more than 750 individuals with type 1 diabetes mellitus (T1DM) have received allogeneic
islet transplants since 1974, in an effort to cure their chronic condition. Though this is still a
small number (especially when ...
Cited by 103 - Related articles - BL Direct - All 11 versions

Insulin secretion in type 1 diabetes


C Steele, WA Hagopian, S Gitelman, U Masharani, M … - Diabetes, 2004 - Am Diabetes Assoc
Type 1 diabetes, a chronic autoimmune disease, causes destruction of insulin-producing β-cells over
a period of years. Although many markers of the autoimmune process have been described, none can
convincingly predict the rate of ...
Cited by 54 - Related articles - BL Direct - All 4 versions

Islet transplantation is associated with an improvement of cardiovascular function …

- diabetesjournals.org
P Fiorina, C Gremizzi, P Maffi, R Caldara, D Tavano … - Diabetes Care, 2005 - Am Diabetes Assoc
RESULTS—GHb levels were similar in the two groups, whereas the exogenous insulin requirement was
lower in the kidney-islet group with persistent C-peptide secretion. Overall, cardiovascular
parameters improved in the ...
Cited by 44 - Related articles - All 6 versions

Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention …


JM Sosenko, JP Palmer, CJ Greenbaum, J Mahon, … - Diabetes Care, 2006 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Fifty-four DPT-1 participants (22 in the parenteral trial and 32 in
the oral trial) were studied. All had oral glucose tolerance tests (OGTTs) at 6-month intervals from
approximately 30 to 6 months before ...
Cited by 40 - Related articles - BL Direct - All 5 versions

Natural history of β-cell function in type 1 diabetes

- diabetesjournals.org
NA Sherry, EB Tsai, KC Herold - Diabetes, 2005 - Am Diabetes Assoc
Despite extensive and ongoing investigations of the immune mechanisms of autoimmune diabetes in
humans and animal models, there is much less information about the natural history of insulin
secretion before and after the ...
Cited by 37 - Related articles - BL Direct - All 6 versions

Subcutaneous insulin: pharmacokinetic variability and glycemic variability


B Guerci, JP Sauvanet - Diabetes and Metabolism, 2005 - Elsevier
The therapeutic goal in insulin-treated diabetic patients is to maintain on the long-term a tight
glucose control (HbA1 c < 6,5-7% or less) through an insulin regimen which “mimic” the
physiological insulin profile: a ...
Cited by 34 - Related articles - BL Direct - All 3 versions

C-peptide: new findings and therapeutic implications in diabetes


J Wahren - Clinical physiology and functional imaging, 2004 - interscience.wiley.com
In contrast to earlier views, new data indicate that proinsulin C-peptide exerts important
physiological effects and shows the characteristics of an endogenous peptide hormone. C-peptide in
nanomolar concentrations binds ...
Cited by 30 - Related articles - BL Direct - All 5 versions

Temporary preservation of β-cell function by diazoxide treatment in childhood type …

- diabetesjournals.org
E Örtqvist, E Björk, M Wallensteen, J Ludvigsson, J … - Diabetes Care, 2004 - Am Diabetes Assoc
RESULTS—Diazoxide decreased circulating C-peptide concentrations by ∼50%. After cessation of the
treatment, basal and meal-stimulated C-peptide concentrations increased to a maximum at 6 months,
followed by a decline. ...
Cited by 30 - Related articles - BL Direct - All 6 versions

Inhibition of GSK3 promotes replication and survival of pancreatic beta cells


R Mussmann, M Geese, F Harder, S Kegel, U … - Journal of Biological …, 2007 - ASBMB
Recent developments indicate that the regeneration of beta cell function and mass in patients with
diabetes is possible. A regenerative approach may represent an alternative treatment option relative
to current diabetes therapies that ...
Cited by 30 - Related articles - All 7 versions


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