- ►physiology.org JJ Holst - Physiological reviews, 2007 - Am Physiological Soc Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in
the intestinal epithelial endocrine L-cells by differential processing of
proglucagon, the gene which is expressed in these cells. The current ... Cited by 113 - Related articles - BL Direct - All 5 versions
I Franklin, J Gromada, A Gjinovci, S … - Diabetes, 2005 - Am Diabetes Assoc Glucagon, secreted from islet α-cells, mobilizes liver glucose. During
hyperglycemia, glucagon secretion is inhibited by paracrine factors from other
islet cells, but in type 1 and type 2 diabetic patients, this suppression ... Cited by 74 - Related articles - All 4 versions
GS Meneilly, N Greig, H Tildesley, JF … - Diabetes Care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—A total of 16 patients with type 2 diabetes who
were being treated with oral hypoglycemic agents were enrolled. Eight patients
(aged 75 ± 2 years, BMI 27 ± 1 kg/m 2 ) remained on usual ... Cited by 58 - Related articles - BL Direct - All 9 versions
- ►endojournals.org J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ... Cited by 60 - Related articles - BL Direct - All 4 versions
- ►endojournals.org J Dupre, MT Behme, TJ McDonald - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Exendin-4 is a reptilian peptide that activates the mammalian receptor for
truncated glucagon-like peptide 1 (tGLP-1) with relatively prolonged actions.
Exendin-4 and tGLP-1 can reduce blood glucose levels by stimulating insulin ... Cited by 48 - Related articles - All 4 versions
J Dupre - Regulatory peptides, 2005 - Elsevier The remission phase of Type 1 diabetes mellitus is associated with substantial
recovery of β-cell function and with marked improvement of endogenous insulin
responses to meals in the early months after diagnosis, accompanied by ... Cited by 28 - Related articles - All 6 versions
JL Estall, DJ Drucker - Current pharmaceutical design, 2006 - ingentaconnect.com Abstract: Glucagon and the glucagon-like peptides are derived from a common
proglucagon precursor, and regulate en- ergy homeostasis through interaction
with a family of distinct G protein coupled receptors. Three ... Cited by 26 - Related articles - BL Direct - All 5 versions
JP Chanoine, KJ Mackelvie, SI Barr, ACK … - Obesity, 2008 - nature.com Scavenger receptor class BI (SR-BI), authentic high-density lipoprotein (HDL)
receptors expressed in liver, are known to play an important role in
HDL-cholesterol (C) metabolism and reverse cholesterol transport. ... Cited by 6 - Related articles - All 2 versions
NE Mikhail - Endocrine Practice, 2006 - AACE Defective insulin secretion and insulin resistance con- tribute independently to
the development of type 2 dia- betes (1). In addition, type 2 diabetes is
generally charac- terized by inappropriately elevated plasma fasting and ... Cited by 6 - Related articles - BL Direct - All 2 versions
N Mikhail - Southern Medical Journal, 2006 - pdfs.journals.lww.com Abstract: Exenatide (synthetic exendin-4) is the analog of gluca- gon-like
peptide 1 (GLP-1), the major physiologic incretin. The latter is an intestinal
hormone that enhances glucose-induced insulin secretion after meals. In ... Cited by 6 - Related articles - BL Direct - All 5 versions
