- ►endojournals.org JM Fernandez-Real, W Ricart - Endocrine Reviews, 2003 - Endocrine Soc Insulin resistance is increasingly recognized as a chronic, low-level,
inflammatory state. Hyperinsulinemia and insulin action were initially proposed
as the common preceding factors of hypertension, low high-density ... Cited by 430 - Related articles - BL Direct - All 5 versions
- ►endojournals.org E Bugianesi, U Pagotto, R Manini, E Vanni, A … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc When the data from all subjects were combined, plasma adiponectin levels were
positively associated with increased age, female gender, and plasma high-density
lipoprotein levels, and negatively associated with waist circumference, ... Cited by 138 - Related articles - All 5 versions
HK Vincent, AG Taylor - International Journal of Obesity, 2005 - nature.com Oxidative stress may be the unifying mechanism underlying the development of
comorbidities in obesity. Evidence suggests that a clustering of sources of
oxidative stress exists in obesity: hyperglycemia, hyperleptinemia, ... Cited by 91 - Related articles - BL Direct - All 5 versions
E Bugianesi, C Zannoni, E Vanni, R … - Digestive and Liver Disease, 2004 - Elsevier The role of insulin resistance in non-alcoholic fatty liver disease is suggested
by laboratory data (hyperinsulinemia and decreased sensitivity to endogenous and
exogenous insulin). The clinical association with features of the metabolic ... Cited by 88 - Related articles - All 6 versions
C Weigert, K Brodbeck, H Staiger, C Kausch, … - Journal of Biological Chemistry, 2004 - ASBMB Circulating interleukin-6 (IL-6), insulin, and free fatty acid (FFA)
concentrations are associated with impaired insulin action in obese and type 2
diabetic individuals. However, a causal relationship between elevated ... Cited by 83 - Related articles - BL Direct - All 4 versions
RK Avramoglu, H Basciano, K Adeli - Clinica chimica acta, 2006 - Elsevier Insulin resistant states are commonly associated with an atherogenic
dyslipidemia that contributes to significantly higher risk of atherosclerosis
and cardiovascular disease. Indeed, disorders of carbohydrate and lipid ... Cited by 58 - Related articles - All 3 versions
- ►ajcn.org C Klein-Platat, J Drai, M Oujaa, JL … - American Journal of Clinical Nutrition, 2005 - Am Soc Nutrition 2 Supported by grants from the Regime Local of the Caisse Regionale d'Assurance
Maladie d'Alsace-Moselle, of the French Public Authorities within the framework
of PNNS and of INSERM. ... Background: Together with adiposity, plasma ... Cited by 56 - Related articles - BL Direct - All 9 versions
- ►physiology.org C Weigert, AM Hennige, K Brodbeck, HU … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Previous studies showed an insulin-"desensitizing" action of IL-6 on glycogen
synthesis in hepatocytes. We recently found no inhibition of the proximal steps
of the insulin signal cascade in human skeletal muscle cells. Because these ... Cited by 46 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org H Staiger, K Staiger, N Stefan, HG Wahl, F … - Diabetes, 2004 - Am Diabetes Assoc Obesity-linked insulin resistance is associated with chronic inflammation and
cardiovascular complications. Free fatty acids (FFAs) are prominent candidates
for the molecular link between these disorders. In this study, we ... Cited by 36 - Related articles - BL Direct - All 5 versions
HK Vincent, KE Innes, KR Vincent - Diabetes, obesity & metabolism, 2007 - pt.wkhealth.com Results: Obesity elevates oxidative stress in young, old and clinical
populations as shown by elevations in lipid peroxidation (malondialdehyde,
hydroperoxides, 4-hydroxynonenal, isoprostanes, conjugated dienes) or ... Cited by 26 - Related articles - BL Direct - All 6 versions