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individuals at high risk of both type 2 diabetes and cardiovascular disease
(CVD). Several expert groups have therefore attempted to produce diagnostic ... Cited by 2158 - Related articles - BL Direct - All 11 versions
- ►clinchem.org GM Reaven - Clinical chemistry, 2005 - Am Assoc Clin Chem Values for insulin-mediated glucose disposal vary continuously throughout a
population of apparently healthy individuals, with at least a sixfold variation
between the most insulin sensitive and most insulin resistant of these ... Cited by 247 - Related articles - All 5 versions
G Reaven - Endocrinology and metabolism clinics of North America, 2004 - Elsevier Sensitivity to insulin-mediated glucose disposal varies widely in the population
at large [1]. When insulin-resistant individuals cannot maintain the degree of
hyperinsulinemia needed to overcome the insulin resistance, type 2 diabetes ... Cited by 213 - Related articles - BL Direct - All 5 versions
- ►nih.gov P Lefebvre, G Chinetti, JC Fruchart, B Staels - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig PPARα is a nuclear receptor that regulates liver and skeletal muscle lipid
metabolism as well as glucose homeostasis. Acting as a molecular sensor of
endogenous fatty acids (FAs) and their derivatives, this ligand-activated ... Cited by 206 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org JD Otvos, D Collins, DS Freedman, I … - Circulation, 2006 - Am Heart Assoc Methods and Results— This is a prospective nested case-control study of 364
men with a new CHD event (nonfatal myocardial infarction or cardiac death)
during a 5.1-year (median) follow-up and 697 age-matched controls. Nuclear ... Cited by 145 - Related articles - All 6 versions
- ►jlr.org AC Li, CK Glass - The Journal of Lipid Research, 2004 - ASBMB The nuclear receptor superfamily is composed of transcription factors that
positively and negatively regulate gene expression in response to the binding of
a diverse array of lipid-derived hormones and metabolites. Intense efforts ... Cited by 141 - Related articles - All 4 versions
- ►ahajournals.org JD Brown, J Plutzky - Circulation, 2007 - Am Heart Assoc Peroxisome proliferator–activated receptors (PPARs) are ligand-activated
transcription factors involved in the transcriptional regulation of key
metabolic pathways such as lipid metabolism, adipogenesis, and insulin ... Cited by 104 - Related articles - All 8 versions
MJ Chapman, G Assmann, JC Fruchart, J … - Current Medical Research and Opinion®, 2004 - informahealthcare.com 1Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital
de la Pitié, Paris, France 2Institute of Arteriosclerosis Research and
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- ►asnjournals.org Y Guan - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol Peroxisome proliferator-activated receptors (PPAR) are members of the nuclear
hormone receptor superfamily of ligand-activated transcription factors. Three
PPAR isoforms, designated PPAR , - / , and - , have been identified and ... Cited by 89 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org M Ricote, AF Valledor, CK Glass - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc •Pennachhio LA, Rubin EM. Apolipoprotein A5, a newly identified gene that
affects plasma triglyceride levels in humans and mice. 2003;23:529–534.
•Cullen P, Baetta R, Bellosta S, Bernini F, Chinetti G, Cignarella A, von ... Cited by 85 - Related articles - BL Direct - All 9 versions