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Scholar Results 1 - 10 of about 31 citing Jain: Elevated blood interleukin-6 levels in hyperketonemic type 1 diabetic patients and.... (0.08 sec) 

Hyperglycemia induces monocytic release of interleukin-6 via induction of protein …

- diabetesjournals.org
S Devaraj, SK Venugopal, U Singh, I Jialal - Diabetes, 2005 - Am Diabetes Assoc
Diabetes confers an increased propensity to atherosclerosis. Inflammation is pivotal in
atherogenesis, and diabetes is a proinflammatory state. Interleukin (IL)-6, in addition to inducing
the acute-phase response, contributes to insulin resistance. Monocytes from type 2 ...
Cited by 68 - Related articles - All 5 versions

Increased monocytic activity and biomarkers of inflammation in patients with type 1 …

- diabetesjournals.org
S Devaraj, N Glaser, S Griffen, J Wang-Polagruto, E … - Diabetes, 2006 - Am Diabetes Assoc
Type 1 diabetes is associated with increased vascular complications, and monocytes are pivotal
cells in atherogenesis. However, there are few data on monocyte function and inflammation in
type 1 diabetes. The aim of this study was to compare monocyte function and biomarkers ...
Cited by 54 - Related articles - BL Direct - All 6 versions

Diabetes induces p66shc gene expression in human peripheral blood …

- endojournals.org
E Pagnin, G Fadini, R de Toni, A Tiengo, L Calo … - Journal of Clinical …, 2005 - Endocrine Soc
Oxidative stress plays a role in cardiovascular dysfunction. This is of interest in diabetes, a clinical
condition characterized by oxidative stress and increased prevalence of cardiovascular
disease. The role of p66 shc in oxidative stress-related response has been demonstrated ...
Cited by 41 - Related articles - All 5 versions

IL-6 and the acute phase response in murine atherosclerosis


L Song, C Schindler - Atherosclerosis, 2004 - Elsevier
Numerous studies have implicated C-reactive protein (CRP) and the acute phase response
(APR) in the development of atherosclerotic heart disease. Interleukin (IL)-6, which regulates
both CRP expression and the APR, has also been identified as a risk factor for heart ...
Cited by 24 - Related articles - All 9 versions

Diabetic ketoacidosis induces in vivo activation of human T-lymphocytes


AE Kitabchi, FB Stentz, GE Umpierrez - Biochemical and Biophysical Research …, 2004 - Elsevier
Diabetic ketoacidosis (DKA) is an inflammatory state associated with immune responses in polymorphonuclear
cells (PMN). Activation of subgroup of T-lymphocytes in PMN of DKA patients, however, is not
known. We studied in vivo activation of CD4 and CD8 lymphocytes by measuring de novo ...
Cited by 21 - Related articles - All 4 versions

Effect of chromium niacinate and chromium picolinate supplementation on lipid …


SK Jain, JL Rains, JL Croad - Free Radical Biology and Medicine, 2007 - Elsevier
Chromium (Cr 3+ ) supplementation facilitates normal protein, fat, and carbohydrate
metabolism, and is widely used by the public in many countries. This study examined the effect
of chromium niacinate (Cr-N) or chromium picolinate (Cr-P) supplementation on lipid ...
Cited by 17 - Related articles - All 3 versions

Acetoacetate activation of extracellular signal-regulated kinase 1/2 and p38 …

- aspetjournals.org
MA Abdelmegeed, SK Kim, KJ Woodcroft, RF … - Journal of Pharmacology …, 2004 - ASPET
Diabetes is characterized by elevated levels of ketone bodies acetoacetate (AA) and 3-hydroxybutyrate
(3HB). High levels of ketone bodies have been implicated in generation of cellular oxidative
stress. Ketone body activation of cellular signaling pathways associated with oxidative ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Evidence of increased inflammation and microcirculatory abnormalities in patients …

- diabetesjournals.org
S Devaraj, AT Cheung, I Jialal, SC Griffen, D Nguyen, … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—Type 1 diabetes is associated with increased microvascular complications and
inflammation. The monocyte-macrophage is a pivotal cell in atherogenesis. There are scanty
data on noninvasive measures of microvascular abnormalities and inflammation in type 1 ...
Cited by 14 - Related articles - BL Direct - All 5 versions

High glucose induces toll-like receptor expression in human monocytes: …

- diabetesjournals.org
MR Dasu, S Devaraj, L Zhao, DH Hwang, I Jialal - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Pharmacological inhibition of protein kinase C (PKC) activity and NADPH oxidase
significantly decreased TLR2 and TLR4 mRNA and protein (P < 0.05). Knocking down both TLR2
and TLR4 in the cells resulted in a 76% (P < 0.05) decrease in high-glucose–induced ...
Cited by 15 - Related articles - All 6 versions

Relationship between adiponectin levels, acylated ghrelin levels, and short-term …

- eje-online.org
GA Martos-Moreno, V Barrios, L Soriano-Guillen, J … - European journal of …, 2006 - EFES
Results: BMI was decreased at diagnosis, normalized at 1 month, and remained so
thereafter. Adiponectin levels at diagnosis were similar to controls, increasing significantly after
1 month and normalizing at 4 months. Acylated ghrelin levels were lower at diagnosis, ...
Cited by 11 - Related articles - BL Direct - All 9 versions


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