DJ Angiolillo, A Fernandez-Ortiz, E Bernardo … - Diabetes, 2005 - Am Diabetes Assoc To assess platelet function profiles in diabetic and nondiabetic patients on
aspirin and clopidogrel therapy, two patient populations were included to
investigate the 1) acute effects of a 300-mg clopidogrel loading dose ... Cited by 120 - Related articles - BL Direct - All 5 versions
C Watala, J Golanski, J Pluta, M Boncler, M … - Thrombosis research, 2004 - Elsevier Aspirin (acetylsalicylic acid, ASA), which is recommended for primary and
secondary prevention in diabetes mellitus (DM), has been shown to have a lower
antiplatelet activity in diabetic patients. We conducted a crossover ... Cited by 88 - Related articles - All 8 versions
- ►onlinejacc.org DJ Angiolillo, E Bernardo, C Ramírez, MA … - Journal of the American College of Cardiology, 2006 - Elsevier Insulin inhibits platelet aggregation by suppressing the P2Y 12 pathway.
However, T2DM patients have a loss of responsiveness to insulin that leads to
upregulation of the P2Y 12 pathway, increased platelet reactivity, and ... Cited by 79 - Related articles - BL Direct - All 23 versions
- ►ahajournals.org W Ageno, C Becattini, T Brighton, R Selby, … - Circulation, 2008 - Am Heart Assoc Methods and Results— Medline and EMBASE databases were searched to identify
studies that evaluated the prevalence of major cardiovascular risk factors in
VTE patients and control subjects. Studies were selected using a priori ... Cited by 67 - Related articles - All 9 versions
- ►onlinejacc.org DJ Angiolillo, E Bernardo, M Sabaté, P … - Journal of the American College of Cardiology, 2007 - Elsevier Type 2 diabetes mellitus patients have increased platelet reactivity compared
with nondiabetic patients. Whether HPR assessed in T2DM while in their
steady-state phase of dual antiplatelet therapy is associated with an ... Cited by 62 - Related articles - BL Direct - All 33 versions
DJ Angiolillo, A Fernandez-Ortiz, E Bernardo … - Diabetes, 2006 - Am Diabetes Assoc Inhibition of the P2Y 12 pathway by the platelet antagonist clopidogrel is
associated with a marked reduction in platelet reactivity. Recent reports have
shown that P2Y 12 inhibition has anti-inflammatory effects as well. ... Cited by 52 - Related articles - BL Direct - All 6 versions
C Watala, J Pluta, J Golanski, M Rozalski, M … - Journal of Molecular Medicine, 2005 - Springer Page 1. J Mol Med (2005) 83:148–158 DOI 10.1007/s00109-004-0600-x ORIGINAL
ARTICLE Cezary Watala · Justyna Pluta · Jacek Golanski ... Cited by 49 - Related articles - All 4 versions
S Fateh-Moghadam, U Plöckinger, N Cabeza, … - Acta Diabetologica, 2005 - Springer Cardiovascular complications are still the leading cause of death among patients
with type 2 diabetes, accounting for 70% of all case fatalities [1, 2]. Numerous
patho- physiological mechanisms have been proposed to explain the ... Cited by 45 - Related articles - All 3 versions
- ►onlinejacc.org C Berry, JC Tardif, MG Bourassa - Journal of the American College of Cardiology, 2007 - Elsevier Diabetes mellitus (DM) is a worldwide epidemic. Its prevalence is rapidly
increasing in both developing and developed countries. Coronary heart disease
(CHD) is highly prevalent and is the major cause of morbidity and mortality ... Cited by 44 - Related articles - BL Direct - All 21 versions
GI Varughese, J Tomson, GYH Lip - International Journal of Clinical Practice, 2005 - interscience.wiley.com Diabetes mellitus is a disease, which is at the epitome of cardiovascular risk
factors causing considerable morbidity and mortality. In addition to
microvascular complications, there is two- to six-fold increased risk of ... Cited by 41 - Related articles - All 4 versions
