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Scholar Results 1 - 10 of about 136 citing Ryan: Short-term intensive insulin therapy in newly diagnosed type 2 diabetes. (0.08 sec) 

Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is …


Y Li, W Xu, Z Liao, B Yao, X Chen, Z Huang, … - Diabetes Care, 2004 - Am Diabetes Assoc
RESULTS—Optimal glycemic control was achieved within 6.3 ± 3.9 days by CSII
in 126 patients. The remission rates (percentages maintaining near euglycemia)
at the third, sixth, twelfth, and twenty-fourth month were 72.6, 67.0, ...
Cited by 120 - Related articles - BL Direct - All 8 versions

{beta}-Cell Failure in Diabetes and Preservation by Clinical Treatment

- endojournals.org
BL Wajchenberg - Endocrine reviews, 2007 - Endocrine Soc
There is a progressive deterioration in ß-cell function and mass in type 2
diabetics. It was found that islet function was about 50% of normal at the time
of diagnosis, and a reduction in ß-cell mass of about 60% was shown at ...
Cited by 105 - Related articles - BL Direct - All 7 versions

Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with …

- dminsulinpump.co.kr [PDF] 
J Weng, Y Li, W Xu, L Shi, Q Zhang, D Zhu, Y … - The Lancet, 2008 - Elsevier
382 patients, aged 25–70 years, were enrolled from nine centres in China
between September, 2004, and October, 2006. The patients, with fasting plasma
glucose of 7·0–16·7 mmol/L, were randomly assigned to therapy with ...
Cited by 52 - Related articles - All 25 versions

Metabolic memory in diabetes-focus on insulin


D LeRoith, V Fonseca, A Vinik - Diabetes/Metabolism Reviews - interscience.wiley.com
Large-scale clinical trials have demonstrated that metabolic control achieved
early in the course of diabetes substantially reduces development and
progression of diabetes and the associated microvascular complications. ...
Cited by 47 - Related articles - All 3 versions

Early use of insulin in type 2 diabetes


R Eldor, E Stern, Z Milicevic, I Raz - Diabetes research and clinical practice, 2005 - Elsevier
Type 2 diabetes is a disease characterised by peripheral insulin resistance, as
well as by pancreatic beta cell dysfunction. This process is in part due to
elevated blood glucose and free fatty acids – termed glucolipotoxicity. ...
Cited by 23 - Related articles - All 9 versions

Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: …


LE Fridlyand, LH Philipson - Current Diabetes Reviews, 2006 - ingentaconnect.com
Abstract: Insulin resistance (IRe) and a failure of insulin secretion are the
major features of the early pathophysiology of type-2 diabetes mellitus (T2D)
but the etiology is still not well understood. We suggest that: 1. The ...
Cited by 15 - Related articles - BL Direct - All 2 versions

Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt …


ZZ Chong, YC Shang, K Maiese - Current neurovascular research, 2007 - pubmedcentral.nih.gov
Impacting a significant portion of the world's population with increasing
incidence in minorities, the young, and the physically active, diabetes mellitus
(DM) and its complications affect approximately 20 million individuals in ...
Cited by 16 - Related articles - BL Direct - All 3 versions

Insulin therapy in people who have dysglycemia and type 2 diabetes mellitus: can it offer …


HC Gerstein, J Rosenstock - Endocrinology and metabolism clinics of North America, 2005 - Elsevier
There is growing recognition that the rapid rise in the prevalence of diabetes
mellitus and lesser degrees of dysglycemia, in concert with the high levels of
associated risk factors for cardiovascular (CV) disease, presages a global ...
Cited by 14 - Related articles - All 3 versions

Treating postprandial hyperglycemia does not appear to delay progression of early type 2 …


MS Kirkman, RR Shankar, S Shankar, C Shen, … - Diabetes Care, 2006 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Two hundred nineteen subjects with early diabetes
were randomly assigned to 100 mg acarbose tid or identical placebo and followed
for 5 years or until they reached the primary outcome (two consecutive ...
Cited by 13 - Related articles - BL Direct - All 5 versions

Early insulin therapy for type 2 diabetic patients: more cost than benefit

- diabetesjournals.org
MB Davidson - Diabetes Care, 2005 - Am Diabetes Assoc
Let me start by summarizing what we (think we) know and don't know that pertains
to this issue. In the mid-1960s (when I was a fellow), the conventional wisdom
was that the complications of diabetes were unrelated to glycemic control; ...
Cited by 13 - Related articles - All 4 versions


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