V Bril, RA Buchanan - Diabetes Care, 2004 - Am Diabetes Assoc OBJECTIVE—The primary purpose of this investigation was to determine whether AS-3201,
a new aldose reductase inhibitor, penetrates the sural nerve and inhibits sorbitol and fructose
accumulation in patients with diabetic sensorimotor polyneuropathy (DSP). An additional ... Cited by 49 - Related articles - BL Direct - All 7 versions
V Bril, RA Buchanan - Diabetes Care, 2006 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Patients with mild to moderate DSP, as determined
by the presence of sural nerve responses, were enrolled in a double-blind, placebo-controlled
biopsy trial and randomized to placebo or 5 or 20 mg/day ranirestat for 12 weeks. Patients ... Cited by 45 - Related articles - BL Direct - All 6 versions
BA Perkins, V Bril - Current Diabetes Reviews, 2005 - ingentaconnect.com Abstract: This paper reviews emerging interventions from the recent clinical literature that demonstrate
the potential for effectiveness in the therapy of the diverse forms of diabetic neuropathy. Diabetic
sensorimotor polyneuropathy is the primary focus of this review given that it is the most ... Cited by 3 - Related articles - BL Direct - All 2 versions
LB Dahlin, F Lithner, LE Bresater, NOB … - Acta Neurologica …, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Related articles - All 3 versions
N Giannoukakis - Expert Opin. Investig. Drugs, 2008 - informahealthcare.com Background: There are currently very few drugs available to directly treat diabetic
complications. Those that are indicated clinically provide symptomatic relief and do not address
the underlying biochemical problems. The involvement of the sorbitol pathway in ... Related articles - BL Direct - All 7 versions
HJ Sim, JS Jeong, HJ Kwon, TH Kang, HM Park, … - … of Chromatography B, 2009 - Elsevier This study describes the optimal analytical conditions for sorbitol analysis by a high-performance
anion-exchange chromatography-pulsed amperometric detection method. Its clinical utility as
a diagnostic tool was established by measuring sorbitol in the sciatic nerves or salivary ... Related articles - All 2 versions
B Vera Bril - jhasim.com Neuropathy is a common diabetic microvascu- lar complication, which can be associated with
sig- nificant positive symptoms for the patient, such as numbness, prickling, aching pain, burning
pain, lancinating pain, or allodynia, and in advanced cases, may eventually lead to ... Related articles - All 3 versions