- ►shouxi.net I Bogacka, H Xie, GA Bray, SR Smith - Diabetes, 2005 - Am Diabetes Assoc Thiazolidenediones such as pioglitazone improve insulin sensitivity in diabetic
patients by several mechanisms, including increased uptake and metabolism of
free fatty acids in adipose tissue. The purpose of the present study was to ... Cited by 118 - Related articles - All 5 versions
- ►endojournals.org ME Trujillo, PE Scherer - Endocrine reviews, 2006 - Endocrine Soc The endocrine functions of the adipose organ are widely studied at this stage.
The adipose organ, and in particular adipocytes, communicate with almost all
other organs. Although some adipose tissue pads assume the functions as ... Cited by 114 - Related articles - BL Direct - All 9 versions
- ►endojournals.org AM Sharma, B Staels - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Conclusions: PPAR is highly expressed in adipose tissue, where its activation
with thiazolidinediones alters fat topography and adipocyte phenotype and
up-regulates genes involved in fatty acid metabolism and triglyceride ... Cited by 98 - Related articles - BL Direct - All 3 versions
- ►nih.gov K Nagashima, C Lopez, D Donovan, C Ngai, N … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Elevated plasma levels of VLDL triglycerides (TGs) are characteristic of
patients with type 2 diabetes mellitus (T2DM) and are associated with increased
production rates (PRs) of VLDL TGs and apoB. Lipoprotein lipase–mediated ... Cited by 86 - Related articles - All 8 versions
- ►diabetesjournals.org JPH van Wijk, EJP de Koning, M Castro … - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS—Rosiglitazone did not change fasting plasma triglycerides compared
with placebo (1.97 ± 0.22 vs. 1.88 ± 0.20 mmol/l, respectively) but decreased
postprandial triglyceride levels, leading to significantly lower ... Cited by 63 - Related articles - All 7 versions
- ►anabolicx.com [PDF] BS Ko, SB Choi, SK Park, JS Jang, YE Kim, S … - Biological & pharmaceutical bulletin, 2005 - J-STAGE ([C 20 H 18 NO 4 ] ), one of the main constituents of CR and Cortex
Phellodendri, is a type of isoquinoline alkaloid, sug- gesting that it is a
candidate of the principal anti-diabetic constituents of CR. According to ... Cited by 50 - Related articles - BL Direct - All 14 versions
A Hammarstedt, CX Andersson, V Rotter … - Prostaglandins, Leukotrienes & Essential Fatty Acids, 2005 - Elsevier Insulin resistance is frequently accompanied by obesity and both obesity and
type 2 diabetes are associated with a mild chronic inflammation. Elevated levels
of various cytokines, such as TNF-α and IL-6, are typically found in the ... Cited by 48 - Related articles - All 6 versions
- ►endojournals.org I Bogacka, B Ukropcova, M McNeil, JM Gimble … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Results: The treatment of adipocytes with forskolin increased mitochondrial copy
number and the expression of genes involved in mitochondrial biogenesis (PPAR
coactivator 1 and transcriptional factor A) and fatty acid oxidation (PPAR ... Cited by 50 - Related articles - BL Direct - All 5 versions
B Pourcet, JC Fruchart, B Staels, C Glineur - Expert Opin. Emerging Drugs, 2006 - informahealthcare.com More than 70% of patients with Type 2 diabetes mellitus (T2DM) die because of
cardiovascular diseases. Current therapeutic strategies are based on separate
treatment of insulin resistance and dyslipidaemia. Development of drugs ... Cited by 40 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org HKR Karlsson, K Hällsten, M Björnholm, H … - Diabetes, 2005 - Am Diabetes Assoc The effect of metformin or rosiglitazone monotherapy versus placebo on insulin
signaling and gene expression in skeletal muscle of patients with newly
diagnosed type 2 diabetes was determined. A euglycemic-hyperinsulinemic ... Cited by 34 - Related articles - All 6 versions
