- ►jbc.org MJ Boucher, L Selander, L Carlsson, H … - Journal of Biological Chemistry, 2006 - ASBMB The transcription factor IPF1/PDX1 plays a crucial role in both pancreas
development and maintenance of -cell function. Targeted disruption of this
transcription factor in -cells leads to diabetes, whereas reduced ... Cited by 25 - Related articles - BL Direct - All 7 versions
MA Karim, X Wang, TC Hale, SC Elbein - BMC Medical Genetics, 2005 - biomedcentral.com We identified 8 variants in the two populations, including a 3 bp insertion in
exon 2 (InsCCG243) in African Americans that resulted in an in-frame proline
insertion in the transactivation domain. No variant was associated with ... Cited by 12 - Related articles - Cached - All 8 versions
C Gragnoli, V Stanojevic, A Gorini, GM Von … - Metabolism, 2005 - Elsevier Maturity-onset diabetes of the young (MODY) is a monogenic autosomal-dominant
form of diabetes mellitus with onset before 25 years of age. Genetic variation
in insulin promoter factor-1 (IPF1) (MODY4) is uncommon but may contribute ... Cited by 11 - Related articles - All 10 versions
K Aston-Mourney, N Wong, M Kebede, S Zraika … - Diabetologia, 2007 - Springer Page 1. ARTICLE Increased nicotinamide nucleotide transhydrogenase levels predispose
to insulin hypersecretion in a mouse strain susceptible to diabetes ... Cited by 10 - Related articles - BL Direct - All 2 versions
- ►jbc.org K Eto, V Kaur, MK Thomas - Journal of Biological Chemistry, 2007 - ASBMB The homeodomain transcription factor pancreas duodenum homeobox-1 (PDX-1) is a
key regulator of pancreatic -cell development, function, and survival. Deficits
in PDX-1 expression result in insulin deficiency and hyperglycemia. We ... Cited by 5 - Related articles - All 6 versions
MN Weedon, TM Frayling - Current Diabetes Reports, 2007 - Springer Introduction Maturity-onset diabetes of the young (MODY) is a type of
non–insulin-dependent diabetes mellitus caused by rare autosomal-dominant
mutations, accounting for 1% to 2% of diabetes cases. Patients with MODY ... Cited by 2 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org SC Elbein, X Wang, MA Karim, BI Freedman, … - Diabetes, 2006 - Am Diabetes Assoc African Americans have twice the prevalence of type 2 diabetes as Caucasians and
much greater genetic diversity. We identified an inframe insertion of a proline
in the insulin promoter factor 1 (IPF1) gene (InsCCG243), which was ... Cited by 2 - Related articles - BL Direct - All 5 versions
K Eto, V Kaur, MK Thomas - Journal of Biological Chemistry, 2006 - ASBMB The homeodomain transcription factor pancreas duodenum homeobox-1 (PDX-1) is a
key regulator of pancreatic beta-cell development, function, and survival.
Deficits in PDX-1 expression result in insulin deficiency and ... Related articles - All 2 versions
O Rubio-Cabezas - Pediatric Diabetes, 2009 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Related articles - All 2 versions