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Scholar Results 1 - 10 of 10 citing Sivenius: Aldose reductase gene polymorphisms and peripheral nerve function in patients with.... (0.12 sec) 

Aldose reductase, still a compelling target for diabetic neuropathy


PJ Oates - Current drug targets, 2008 - ingentaconnect.com
Abstract: Aldose reductase (AR) enzymatically transforms cytosolic glucose into
sorbitol, a molecule that poorly pene- trates cell membranes and is sometimes
slowly metabolized. Hyperglycemia can cause intracellular accumulation of ...
Cited by 26 - Related articles - BL Direct - All 3 versions

Decline in neurophysiological function after 7 years in an adolescent diabetic cohort and …

- diabetesjournals.org
K Thamotharampillai, AKF Chan, B Bennetts, … - Diabetes care, 2006 - Am Diabetes Assoc
RESULTS—Median time between first and last assessment was 7.0 years
(interquartile range 5.1–11.1), with a median of five assessments (four to
seven) per individual. At first assessment, median age was 12.7 years ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Diabetic neuropathies: unanswered questions


Y Harati - Neurologic clinics, 2007 - Elsevier
Diabetic neuropathies are the most common types of neuropathies worldwide.
Although there has been significant progress in the understanding of the
clinical aspects of these conditions, many questions remain unanswered or ...
Cited by 5 - Related articles - All 4 versions

Aldose reductase gene is associated with diabetic macroangiopathy in Japanese Type 2 …


A Watarai, E Nakashima, Y Hamada, G … - Diabetic Medicine, 2006 - pubmedcentral.nih.gov
There were no significant differences in genotypic or allelic distribution in
patients with or without ischaemic heart diseases, but there was a significant
increase in the frequency of the CT + TT genotype and T allele in patients ...
Cited by 2 - Related articles - BL Direct - All 8 versions

醛糖还原酶: 心肌缺血损伤干预的新靶点


王俊杰, 康桢, 杨天崙 - 国际病理科学与临床杂志, 2007 - 万方数据资源系统
醛糖还原酶是糖代谢多元醇通路的限速酶.最新研究表明:心肌缺血时醛糖还原酶活性增强,抑制
醛糖还原酶可以通过保护糖酵解途径和抑制氧化应激,减轻心肌缺血损伤,改善缺血再灌注 ...
Cited by 1 - Related articles - All 3 versions

Genomics of Diabetic Neuropathy


AG Demaine, B Yang - Diabetic Neuropathy: Clinical Management, 2007 - Springer
SUMMARY Diabetes is associated with considerable mortality and morbidity due to
the long term complications of the disease. Diabetic neuropathy is a major
complication of diabetes and there is increasing evidence to implicate ...
Related articles - All 3 versions

Pathogenesis of Human Diabetic Neuropathy


RA Malik, PG Newrick, AK Sharma, DR … - Diabetic Neuropathy: Clinical Management, 2007 - Springer
Experimental studies have provided multiple mechanisms for the development of
diabetic neuropathy, yet very few findings have been replicated in patients.
Hyperglycemia mediated nerve damage may begin very early even prior to ...
Related articles - All 3 versions

Thienocinnolinone Alkanoic Acid Derivatives as Aldose Reductase Inhibitors


A Pau, B Asproni, G Murineddu, G Boatto, GE … - Medicinal Chemistry, 2006 - ingentaconnect.com
A. Pau *,1 , B. Asproni 1 , G. Murineddu 1 , G. Boatto 1 , GE Grella 1 , D.
Rakowitz 2 , L. Costantino 3 and ... 1 Dipartimento Farmaco Chimico
Tossicologico,Università di Sassari, Via Muroni 23/A, 07100 Sassari, Italy;
Related articles - BL Direct - All 2 versions

醛糖还原酶及其遗传多态性与糖尿病慢性并发症的相关性


程欢莲, 欧阳冬生 - 中国临床药理学与治疗学, 2009 - cqvip.com
首页; 期刊大全; 知识社区; 学者空间; 学术机构; 专题导读; 充值中心.
客服中心. 维普资讯 中文期刊·专业文章. 维普专业检索. ...
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[PDF] 제 2 형 당뇨병환자에서 알도스 환원효소 유전자의 (AC) n 반복다형성과 당뇨병성 신경병증 …


정인경, 박경수, 문민경, 김재현, 신찬수, … - 210.101.116.17
Page 1. 당뇨병 제 31 권 제 3 호, 2007 원 저 274 제2형 당뇨병환자에서
알도스 환원효소 유전자의 (AC)n 반복다형성과 ...
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