- ►endojournals.org BL Wajchenberg - Endocrine reviews, 2007 - Endocrine Soc There is a progressive deterioration in ß-cell function and mass in type 2 diabetics. It was found
that islet function was about 50% of normal at the time of diagnosis, and a reduction in ß-cell
mass of about 60% was shown at necropsy. The reduction of ß-cell mass is attributable to ... Cited by 105 - Related articles - BL Direct - All 7 versions
T Staeva-Vieira, M Peakman, M Von … - Clinical and …, 2007 - pubmedcentral.nih.gov Type 1 diabetes (T1D) is often considered the prototype organ-specific autoimmune disease
in clinical immunology circles. The key disease features − precise destruction of a single endocrine
cell type occurring on a distinct genetic and autoimmune background − have been ... Cited by 48 - Related articles - BL Direct - All 5 versions
G Stenström, A Gottsäter, E Bakhtadze, B Berger, G … - Diabetes, 2005 - Am Diabetes Assoc Latent autoimmune diabetes in adults (LADA) is a disorder in which, despite the presence of
islet antibodies at diagnosis of diabetes, the progression of autoimmune β-cell failure is
slow. LADA patients are therefore not insulin requiring, at least during the first 6 months ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►scielo.br [PDF] CEB Couri, MC Foss, JC Voltarelli - Brazilian Journal of Medical and …, 2006 - SciELO Brasil Type 1 diabetes mellitus results from a cell-mediated autoimmune attack against pancreatic
ß-cells. Traditional treatments involve nu- merous daily insulin dosages/injections and rigorous
glucose control. Many efforts toward the identification of ß-cell precursors have been ... Cited by 22 - Related articles - View as HTML - BL Direct - All 7 versions
- ►endojournals.org T Maruyama, S Tanaka, A Shimada, O Funae, A … - Journal of Clinical …, 2008 - Endocrine Soc Methods: This multicenter, randomized, nonblinded clinical study screened 4089
non-insulin-dependent diabetic patients for glutamic acid decarboxylase autoantibodies
(GADAb). Sixty GADAb-positive non-insulin-requiring diabetic patients with a 5-yr ... Cited by 11 - Related articles - BL Direct - All 4 versions
B Phillips, K Nylander, J Harnaha, J Machen, R … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Microspheres carrying antisense oligonucleotides to
CD40, CD80, and CD86 were delivered into NOD mice. Glycemia was monitored to determine
disease prevention and reversal. In recipients that remained and/or became diabetes ... Cited by 9 - Related articles - All 11 versions
E Jacobson-Dickman, L Levitsky - The Pediatric Clinics of North America, 2005 - Elsevier Most cases of diabetes in childhood are immunologically mediated and eventually lead to complete
insulin deficiency. Oral therapies for children with type 1 autoimmune diabetes mellitus
(T1DM) are experimental and of unproven efficacy. Eight percent to 45% of children with ... Cited by 7 - Related articles - All 10 versions
M Zdravkovic, M Kruse, KL Rost, J Moss, A … - The Journal of Clinical …, 2005 - jcp.sagepub.com On behalf of: American College of Clinical Pharmacology ... 10.1177/0091270005276947 ZDRAVKOVICETAL
EFFECTOFN 414INHEALTHYMALESUBJECTS CLINICALSTUDIES The Effects of NN414, a
SUR1/Kir6.2 ... Milan Zdravkovic, MD, PhD, Matthias Kruse, MD, PhD, Karl Ludwig Rost, ... Cited by 5 - Related articles - BL Direct - All 4 versions
J Ludvigsson - Pediatric Diabetes, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 3 - Related articles - All 2 versions
- ►diabetesjournals.org B Ng, Y Kang, CL Elias, Y He, H Xie, JB Hansen, P … - Diabetes, 2007 - Am Diabetes Assoc Islet β-cell–specific ATP-sensitive K + (K ATP ) channel openers thiadiazine dioxides induce
islet rest to improve insulin secretion, but their molecular basis of action remains unclear. We
reported that syntaxin-1A binds nucleotide binding folds of sulfonylurea receptor 1 ... Cited by 2 - Related articles - BL Direct - All 4 versions
