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Scholar Results 1 - 10 of about 37 citing Arslanian: Family history of type 2 diabetes is associated with decreased insulin sensitivity.... (0.10 sec) 

Contributions of β-cell dysfunction and insulin resistance to the pathogenesis of impaired …

- diabetesjournals.org
MA Abdul-Ghani, D Tripathy, RA DeFronzo - Diabetes Care, 2006 - Am Diabetes Assoc
Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) are
intermediate states in glucose metabolism that exist between normal glucose
tolerance and overt diabetes. Epidemiological studies demonstrate that the ...
Cited by 89 - Related articles - BL Direct - All 5 versions

The metabolic consequences of childhood obesity


R Weiss, S Caprio - Best Practice & Research Clinical Endocrinology & …, 2005 - Elsevier
The prevalence of childhood obesity is increasing worldwide, as is the
prevalence of obesity-related co-morbidity. Altered glucose metabolism,
manifested as impaired glucose tolerance (IGT), appears early in obese ...
Cited by 86 - Related articles - All 17 versions

Type 2 diabetes mellitus in youth: the complete picture to date


N Gungor, T Hannon, I Libman, F Bacha, S … - The Pediatric Clinics of North America, 2005 - Elsevier
Type 2 diabetes mellitus (T2DM) historically was considered a disease of adults,
with autoimmune type 1 diabetes mellitus (T1DM) accounting for almost all cases
of pediatric diabetes. T2DM was recognized as a disease of the pediatric ...
Cited by 44 - Related articles - All 16 versions

Longitudinal study of physiologic insulin resistance and metabolic changes of puberty


TS HANNON, J JANOSKY, SA ARSLANIAN - Pediatric research, 2006 - journals.lww.com
ABSTRACT: Cross-sectional studies have shown that 1) adoles- cents are insulin
resistant compared with prepubertal children and adults, 2) pubertal insulin
resistance is likely mediated by growth hormone (GH), and 3) pubertal ...
Cited by 40 - Related articles - BL Direct - All 3 versions

Family history of type 2 diabetes: A population-based screening tool for prevention?


S Hariri, PW Yoon, N Qureshi, R Valdez, MT … - Genetics in Medicine, 2006 - journals.lww.com
Purpose: To evaluate the use of self-reported family medical history as a
potential screening tool to identify people at-risk for diabetes. Methods: The
HealthStyles 2004 mail survey comprises 4345 US adults who completed a ...
Cited by 35 - Related articles - BL Direct - All 8 versions

Evaluation of family history as a risk factor and screening tool for detecting undiagnosed …


S Hariri, PW Yoon, R Moonesinghe, R Valdez … - Genetics in Medicine, 2006 - journals.lww.com
Purpose: We examined the utility of a three-level familial risk stratification
system as a screening tool for diabetes in a nationally representative sample of
the US adult population. Methods: National Health and Nutrition Examination ...
Cited by 16 - Related articles - BL Direct - All 2 versions

Impaired beta cell glucose sensitivity and whole-body insulin sensitivity as predictors of …


M Walker, A Mari, MK Jayapaul, SMA Bennett, … - Diabetologia, 2005 - Springer
Abstract Aims/hypothesis: The aim of this prospective study was to investigate
predictors of deteriorating glucose tolerance in subjects of British extraction.
Methods: A total of 156 non-diabetic subjects (86 with a family history of ...
Cited by 14 - Related articles - BL Direct - All 5 versions

Prevention and treatment of type 2 diabetes in youth


IM Libman, SA Arslanian - Horm Res, 2007 - content.karger.com
Parallel to the increase in obesity worldwide, there has been a rise in the
prevalence of type 2 diabetes mellitus (T2DM) in children and adolescents. The
etiology of T2DM in youth, similar to adults, is multifactorial including ...
Cited by 15 - Related articles - BL Direct - All 6 versions

Multifaceted therapeutic approaches for a multigenic disease


R Bottino, M Trucco - Diabetes, 2005 - Am Diabetes Assoc
Diabetes is a severe chronic disease that affects ∼200 million individuals
worldwide, with extremely debilitating effects and considerably high health care
costs. The two major classes of diabetes, known as type 1 (previously known ...
Cited by 13 - Related articles - BL Direct - All 6 versions

Insulin-like growth factor-(IGF)-axis, inflammation, and glucose intolerance among older …

- nih.gov
SN Rajpathak, AP McGinn, HD Strickler, TE … - Growth Hormone & IGF Research, 2008 - Elsevier
Increasing evidence suggests that the insulin-like growth factor (IGF)-axis may
play a role in glucose metabolism and may also be associated with systemic
inflammation. The aim of this study was to evaluate the association of ...
Cited by 12 - Related articles - All 5 versions


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