- ►asnjournals.org JF Navarro-Gonzalez, C Mora-Fernandez - Journal of the American …, 2008 - Am Soc Nephrol Cytokines act as pleiotropic polypeptides regulating inflammatory and immune responses through
actions on cells. They provide important signals in the pathophysiology of a range of
diseases, including diabetes mellitus. Chronic low-grade inflammation and activation of ... Cited by 46 - Related articles - All 5 versions
JF Navarro, C Mora-Fernández - Cytokine and Growth Factor Reviews, 2006 - Elsevier Diabetes mellitus and its complications are a public health problem. Diabetic nephropathy has
become the main cause of renal failure, and furthermore is associated with a dramatic increase
in cardiovascular risk. Unfortunately, the mechanisms leading to the development and ... Cited by 33 - Related articles - All 7 versions
C Mora, JF Navarro - Current Diabetes Reports, 2006 - Springer Diabetic nephropathy has become the main cause of renal failure, but unfortunately the intimate
mecha- nisms leading to the development and progression of renal injury are not yet fully
known. Activated innate immunity and inflammation are relevant factors in the ... Cited by 23 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org N Katakami, H Kaneto, M Matsuhisa, K Yoshiuchi, K … - Diabetes care, 2007 - Am Diabetes Assoc Recent studies have shown that low-grade inflammation plays an important role in the development
of diabetes vascular complications (1). Interleukin-18 (IL-18) is well known to play a key role
in various inflammatory and autoimmune diseases (2). IL-18 produces proinflammatory ... Cited by 8 - Related articles - BL Direct - All 7 versions
- ►cardiologicomonzino.it [PDF] D Baldassarre, A de Jong, M Amato, PJ Werba, … - Annals of …, 2008 - informahealthcare.com Background. Different soluble molecules involved in inflammation, endothelial damage, or hemostasis
are recognized as potential cardiovascular risk markers. Studies to assess the role of these markers
in the atherosclerotic process by evaluating their relationship to carotid intima‐media ... Cited by 9 - Related articles - BL Direct - All 7 versions
D Liang, WF Mao, CW Yao, HF Liu, XW Chen - Cell Mol Immunol, 2006 - cmi.ustc.edu.cn To evaluate the balance status of interleukin 18 (IL-18) and interleukin 18 binding protein
(IL-18BP) in circulation in patients with lupus nephritis (LN) and primary nephrotic syndrome
(PNS), plasma levels as well as mRNA expression in peripheral blood mononuclear cells ... Cited by 7 - Related articles - View as HTML - All 2 versions
D Liang, HF Liu, CW Yao, HY Liu, CM Huang-Fu, … - Nephrology, 2007 - interscience.wiley.com Methods: The expressions of IL-18 and IL-18 receptor in TEC were detected by immunohistochemical
staining in vivo and by reverse transcriptase polymerase chain reaction (RT-PCR) in vitro. TEC
line (HK-2 cells) were incubated without or with IL-18. Cell proliferation and cell cycle ... Cited by 5 - Related articles - BL Direct - All 3 versions
S Araki, M Haneda, D Koya, T Sugimoto, K Isshiki, M … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis The early identification of type 2 diabetic patients at risk of developing
microalbuminuria—an inde- pendent risk factor for renal and cardiovascular diseases— is important
to improve the patients' outcomes. We investigated whether serum levels of IL-18, a ... Cited by 6 - Related articles - BL Direct - All 4 versions
H Inoue, K Hiraoka, T Hoshino, M Okamoto, T Iwanaga, … - Bone, 2008 - Elsevier Osteoarthritis (OA) is closely related to the function of several inflammatory cytokines. It has been
reported that older age is associated with higher serum levels of the inflammatory cytokine
IL-18. In the present study, we investigated the long-term role of serum IL-18 in cartilage ... Cited by 2 - Related articles - All 9 versions
P Skopinski, J Szaflik, I Partyka, J Chorostowska- … - … European Journal of …, 2007 - termedia.pl Abstract In our previous study we observed higher in vivo angiogenic activity and interleukin
18 level in sera of elderly patients with diabetes mellitus type 2 (DM2) and background
retinopathy, in comparison to the controls. The aim of the present study was to compare ... Cited by 2 - Related articles - BL Direct - All 4 versions
