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Five-year follow-up after clinical islet transplantation

- diabetesjournals.org
EA Ryan, BW Paty, PA Senior, D Bigam, E Alfadhli, NM … - Diabetes, 2005 - Am Diabetes Assoc
Islet transplantation can restore endogenous β-cell function to subjects with type 1 diabetes.
Sixty-five patients received an islet transplant in Edmonton as of 1 November 2004. Their mean
age was 42.9 ± 1.2 years, their mean duration of diabetes was 27.1 ± 1.3 years, and 57% ...
Cited by 532 - Related articles - All 10 versions

Insulin independence after living-donor distal pancreatectomy and islet …

- uci.edu [PDF] 
S Matsumoto, T Okitsu, Y Iwanaga, H Noguchi, H … - The Lancet, 2005 - Elsevier
Rising demand for islet transplantation will lead to severe donor shortage in the near future, especially
in countries where cadaveric organ donation is scarce. We undertook a successful transplantation
of living-donor islets for unstable diabetes. The recipient was a 27-year-old woman who ...
Cited by 95 - Related articles - All 11 versions

Current status of pancreatic islet transplantation


S Merani, A Shapiro - Clinical Science, 2006 - submit.clinsci.org
Abbreviations: BMI, body mass index; CD40L, CD40 ligand; CITR, Collaborative Islet Transplant
Registry; CTLA4, cytotoxic T-lymphocyte attenuator protein 4; CMV, cytomegalovirus; DCCT,
Diabetes Control and Complications Trial; DM, diabetes mellitus; DP, donor point; FDA, ...
Cited by 40 - Related articles - Cached - BL Direct - All 12 versions

Prediction of clinical outcome in islet allotransplantation


F Bertuzzi, C Ricordi - Diabetes Care, 2007 - Am Diabetes Assoc
Graft function prediction is a work in progress. Initially, the best parameters representative of
engrafted islet mass in recipients should be defined. Fasting C-peptide and exogenous insulin
requirements are commonly used, although other methods for a more complete ...
Cited by 19 - Related articles - All 7 versions

Simple Measures to Monitor [beta]-Cell Mass and Assess Islet Graft Dysfunction.


RN Faradji, K Monroy, S Messinger, A Pileggi, … - American Journal of …, 2007 - ccmjournal.org
C 2006 The Authors Journal compilation C 2006 The American Society of Transplantation and
the American Society of Transplant Surgeons doi: 10.1111/j.1600-6143.2006.01620.x ... Simple
Measures to Monitor b -Cell Mass and Assess ... RN Faradji a,b , K. Monroy a , S. ...
Cited by 20 - Related articles - BL Direct - All 5 versions

Expectations and strategies regarding islet transplantation: Metabolic data from the …


L Badet, PY Benhamou, A Wojtusciszyn, R … - Transplantation, 2007 - journals.lww.com
Transplantation. Wolters Kluwer Health | Lippincott Williams & Wilkins. All Issues. ...
Cited by 17 - Related articles - BL Direct - All 5 versions

Islet cell transplantation

- sld.cu [PDF] 
P Srinivasan, GC Huang, SA Amiel, ND Heaton - British Medical Journal, 2007 - pmj.bmj.com
People with type 1 diabetes have normal exocrine pancreatic function, making islet cell rather
than whole organ transplantation an attractive option. Achieving insulin independence in type
1 diabetes was the perceived goal of islet cell transplantation. The success of the ...
Cited by 12 - Related articles - BL Direct - All 8 versions

Overcoming the challenges now limiting islet transplantation: a sequential, …


A PILEGGI, L COBIANCHI, L INVERARDI, C … - Annals of the New York …, 2006 - cat.inist.fr
Steady improvements in islet cell processing technology and immunosuppressive protocols have
made pancreatic islet transplantation a clinical reality for the treatment of patients with Type diabetes
mellitus(T 1 DM). Recent trials are showing that improved glycemic metabolic control, ...
Cited by 14 - Related articles - BL Direct - All 5 versions

Evaluation of islet transplantation from non-heart beating donors.


H Noguchi, Y Iwanaga, T Okitsu, H Nagata, Y … - American Journal of …, 2006 - ccmjournal.org
O ver the last few decades, we have witnessed numerous re- search findings and new tech-
nologies that help us provide better care to our patients. Unfortunately, the quality of health care
is far from opti- mal (1). There have been urgent calls high- lighting the need to close the ...
Cited by 10 - Related articles - BL Direct - All 6 versions

Islet transplantation: Current status and future directions


B Hatipoglu, E Benedetti, J Oberholzer - Current Diabetes Reports, 2005 - Springer
Introduction: From Banting to the “Edmonton protocol” By the early years of the 20th century,
it was well understood that diabetes mellitus involved the body's inability to metab- olize or utilize
food. It was also understood that the pancreas held the key to carbohydrate metabolism. ...
Cited by 7 - Related articles - BL Direct - All 2 versions


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