- ►shouxi.net PE Cryer - Diabetes, 2005 - Am Diabetes Assoc Iatrogenic hypoglycemia is a problem for people with diabetes. It causes
recurrent morbidity, and sometimes death, as well as a vicious cycle of
recurrent hypoglycemia, precluding maintenance of euglycemia over a ... Cited by 72 - Related articles - BL Direct - All 7 versions
DJ Drucker - Nature Clinical Practice Endocrinology and Metabolism, 2005 - glucagon.com INTRODUCTION Before the cDNAs and genes encoding pro glucagon were cloned,
pancreatic glucagon was the prin- cipal proglucagon-derived peptide (PGDP) with
well-characterized biologic actions. However, antisera directed against ... Cited by 59 - Related articles - View as HTML - BL Direct - All 6 versions
- ►nih.gov N Marty, M Dallaporta, M Foretz, M Emery, D … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Ripglut1;glut2 –/– mice have no endogenous glucose transporter type 2
(glut2) gene expression but rescue glucose-regulated insulin secretion. Control
of glucagon plasma levels is, however, abnormal, with fed hyperglucagonemia ... Cited by 38 - Related articles - BL Direct - All 10 versions
- ►endojournals.org BE Dunning, JE Gerich - Endocrine reviews, 2007 - Endocrine Soc The hyperglycemic activity of pancreatic extracts was encountered some 80 yr ago
during efforts to optimize methods for the purification of insulin. The
hyperglycemic substance was named "glucagon," and it was subsequently ... Cited by 32 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] PE Cryer - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig A reduced sympathoadrenal response, induced by recent antecedent hypoglycemia,
is the key feature of hypoglycemia-associated autonomic failure (HAAF) and,
thus, the pathogenesis of iatrogenic hypoglycemia in diabetes. ... Cited by 17 - Related articles - BL Direct - All 11 versions
- Free from Publisher Z Israelian, NR Gosmanov, E Szoke, M Schorr, … - Diabetes Care, 2005 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Twelve subjects with type 2 diabetes who have been
insulin requiring were studied as a model of advanced β-cell failure. Glucagon
responses were examined during a 90-min hypoglycemic clamp (∼2.8 mmol/l) ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►endojournals.org SM Schmid, M Hallschmid, K Jauch-Chara, N … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Results: Basal glucagon concentrations were decreased (P = 0.022) and C-peptide
levels were slightly reduced after SD (P = 0.085), compared with regular sleep.
During hypoglycemia after SD, the glucagon increase relative to baseline ... Cited by 11 - Related articles - BL Direct - All 7 versions
Z Israelian, E Szoke, J Woerle, S Bokhari, M … - Metabolism, 2006 - Elsevier In type 2 diabetes mellitus (T2DM), little is known about hormonal responses to
hypoglycemia. In particular, beta-cell responses to hypoglycemia have not been
carefully investigated and potentially because of confounding factors or ... Cited by 7 - Related articles - All 10 versions
- ►shouxi.net N Marty, I Bady, B Thorens - Diabetes, 2006 - Am Diabetes Assoc The pancreatic β-cell paradigm for glucose sensing has been proposed to apply
to brain glucose sensors controlling counterregulation to hypoglycemia and
feeding behavior. Over recent years, we tested this model in mice by first ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►physiology.org P Bansal, Q Wang - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Glucose homeostasis is regulated primarily by the opposing actions of insulin
and glucagon, hormones that are secreted by pancreatic islets from β-cells and
-cells, respectively. Insulin secretion is increased in response to ... Cited by 6 - Related articles - All 3 versions
