DJ Drucker, MA Nauck - The Lancet, 2006 - Elsevier Glucagon-like peptide 1 (GLP-1) is a gut-derived incretin hormone that stimulates insulin and
suppresses glucagon secretion, inhibits gastric emptying, and reduces appetite and food
intake. Therapeutic approaches for enhancing incretin action include ... Cited by 416 - Related articles - All 10 versions
P Aschner, MS Kipnes, JK Lunceford, M Sanchez, … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—Sitagliptin 100 and 200 mg produced significant (P < 0.001) placebo-subtracted
reductions in A1C (−0.79 and −0.94%, respectively) and fasting plasma glucose (−1.0
mmol/l [−17.1 mg/dl] and −1.2 mmol/l [−21.3 mg/dl], respectively). Patients with baseline ... Cited by 195 - Related articles - BL Direct - All 13 versions
- ►januvia.se [PDF] I Raz, M Hanefeld, L Xu, C Caria, D Williams-Herman, … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis The aim of this study was to assess the efficacy and safety of sitagliptin
(MK-0431) as mono- therapy in patients with type 2 diabetes mellitus and inadequate glycaemic
control (HbA 1c Q7% and e10%) on exercise and diet. Methods A total of 521 patients ... Cited by 167 - Related articles - All 5 versions
M Bayes, X Rabasseda, JR Prous - Methods and findings in …, 2006 - journals.prous.com Contributing Editors: P. Cole, C. Orellana, JA Vallès, RM a . Antonijoan, KP Mohana Priya,
M. Priya, V. Renuga, R. Sree Lekha, B. Priya, A. Tomillero, G. Krithiga and E. Banu Rekha. Cited by 148 - Related articles - All 9 versions
J Rosenstock, MA Baron, R Camisasca, F … - Diabetes, Obesity …, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 111 - Related articles - All 5 versions
V Fonseca, A Schweizer, D Albrecht, MA Baron, I … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Type 2 diabetes is difficult to manage in patients with a long history
of disease requiring insulin therapy. Moreover, addition of most currently available oral antidiabetic
agents increases the risk of hypoglycaemia. Vildagliptin is a dipeptidyl peptidase-IV ... Cited by 105 - Related articles - BL Direct - All 4 versions
- ►endojournals.org BL Wajchenberg - Endocrine reviews, 2007 - Endocrine Soc There is a progressive deterioration in ß-cell function and mass in type 2 diabetics. It was found
that islet function was about 50% of normal at the time of diagnosis, and a reduction in ß-cell
mass of about 60% was shown at necropsy. The reduction of ß-cell mass is attributable to ... Cited by 105 - Related articles - BL Direct - All 7 versions
A Schweizer, A Couturier, JE Foley, S … - Diabetic Medicine, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 90 - Related articles - BL Direct - All 4 versions
MC Riddle, DJ Drucker - Diabetes Care, 2006 - Am Diabetes Assoc Current therapies for type 2 diabetes are frequently associated with inadequate control of postprandial
hyperglycemia, weight gain, and, in the case of oral agents, loss of efficacy over time. A better
understanding of physiological responses to meals is leading to the development of new ... Cited by 72 - Related articles - BL Direct - All 10 versions
A Barnett - International journal of clinical practice, 2006 - nerdoc.wordpress.com The dipeptidyl peptidase 4 (DPP-4) inhibitors enhance the body's own ability to control blood
glucose by increas- ing the active levels of incretin hormones in the body. Their mechanism of
action is distinct from any existing class of oral glucose-lowering agents. They control ... Cited by 69 - Related articles - View as HTML - BL Direct - All 7 versions
