R Simo, E Carrasco, M Garcia-Ramirez, C … - Current Diabetes …, 2006 - ingentaconnect.com Abstract: Diabetic retinopathy continues to be the leading cause of legal blindness among
working-age individuals. The earliest histological features of diabetic retinopathy include neuroretinal
damage, capillary basement membrane thickening, loss of pericytes and loss of ... Cited by 37 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org E Carrasco, C Hernández, A Miralles, P Huguet, J … - Diabetes Care, 2007 - Am Diabetes Assoc RESULTS—A higher expression of SST was detected in RPE than neuroretina in both
groups. SST mRNA levels and SST-28 immunoreactivity were significantly lower in both RPE
and the neuroretina from diabetic donors compared with nondiabetic donors. These ... Cited by 11 - Related articles - BL Direct - All 4 versions
C Hernández, R Simó - Expert Opinion in Investigational Drugs, 2007 - informahealthcare.com Proliferative diabetic retinopathy (PDR) demands both more effective and less expensive biologically
based treatments. Our understanding of the pathophysiology of the disease is increasing as
new biochemical pathways are identified. Most reports emphasize proangiogenic stimuli, ... Cited by 10 - Related articles - BL Direct - All 5 versions
SS Palii, S Caballero Jr, G Shapiro, … - Expert Opin. Investig. …, 2007 - informahealthcare.com Traditional management strategies for retinal neovascularisation accompanying proliferative
diabetic retinopathy include photocoagulation laser therapy. The development of preventative
pharmacological treatments aimed at replacing or delaying this acute intervention has ... Cited by 9 - Related articles - BL Direct - All 4 versions
R Simó, E Carrasco, A Fonollosa, J García-Arumí, R … - Diabetes care, 2007 - Am Diabetes Assoc Although diabetic macular edema (DME) is the main cause of visual loss in type 2 diabetic patients
(1), its pathogenic mechanisms have been much less studied than proliferative diabetic retinopathy
(PDR). The production of both somatostatin (SST) and its receptors by the retina suggests ... Cited by 9 - Related articles - BL Direct - All 5 versions
E Carrasco, C Hernández, I de Torres, J Farrés, … - Molecular …, 2008 - pubmedcentral.nih.gov Cortistatin (CST), a neuropeptide with strong structural and functional similarities to
somatostatin, is abundant in the vitreous fluid, and it is decreased in patients with proliferative
diabetic retinopathy. The aims of the present study were to explore whether the retina ... Cited by 3 - Related articles - All 6 versions
J Garcí-Arumí, A Fonollosa, C Macià, C Hernandez, V … - Eye, 2008 - nature.com In a recent study, we found high levels of erythropoietin (EPO) in patients with diabetic macular
oedema (DME), suggesting a role of EPO in the pathogenesis of this condition. To investigate
a possible relationship between EPO and other diseases causing macular oedema, we ... Cited by 1 - Related articles - All 3 versions
AA Rao, H Thota, RS Gumpeny, A Akula, SB … - Medical Hypotheses, 2008 - Elsevier Diabetic retinopathy is the leading cause of blindness among patients with diabetes mellitus.
We evaluated the role of several proteins that are likely to be involved in diabetic retinopathy
by employing multiple sequence alignment using ClustalW tool and constructed a ... Cited by 1 - Related articles - All 27 versions
T Missotten, JAM van Laar, TL van der Loos, PLA … - American Journal of …, 2007 - Elsevier In 20 patients, 20 episodes of recurrent CME during otherwise quiescent uveitis were treated
with intramuscular octreotide LAR injections. Patients were included if CME control with acetazolamide
or systemic and periocular steroids had failed during previous CME episodes or if ... Cited by 1 - Related articles - All 28 versions
