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Scholar Results 1 - 10 of about 120 citing Gillespie: The impact of ACE inhibitors or angiotensin II type 1 receptor blockers on the.... (0.07 sec) 

Incident diabetes in clinical trials of antihypertensive drugs: a network meta- …


WJ Elliott, PM Meyer - The Lancet, 2007 - Elsevier
Intitial drug therapy used in the trials (and the number of patients with diabetes of the total number
at risk) included: an ARB (1189 of 14 185, or 8·38%), ACE inhibitor (1618 of 22 941, or
7·05%), calcium-channel blocker (CCB, 2791 of 38 607, or 7·23%), placebo (1686 of 24 ...
Cited by 300 - Related articles - BL Direct - All 17 versions

Renin-angiotensin system and cardiovascular risk


RE Schmieder, KF Hilgers, MP Schlaich, BMW Schmidt - The Lancet, 2007 - Elsevier
The renin-angiotensin system is a major regulatory system of cardiovascular and renal
function. Basic research has revealed exciting new aspects, which could lead to novel or modified
therapeutic approaches. Renin-angiotensin system blockade exerts potent ...
Cited by 132 - Related articles - All 20 versions

Angiotensin receptor blockers may increase risk of myocardial infarction: …

- ahajournals.org
MH Strauss, AS Hall - Circulation, 2006 - Am Heart Assoc
Angiotensin-converting enzyme inhibitors (ACEIs) play an important role in the management
of patients at increased cardiovascular (CV) risk. ACEIs reduce both myocardial infarction
(MI) and mortality in patients with symptomatic congestive heart failure or asymptomatic ...
Cited by 82 - Related articles - All 7 versions

Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults …

- tmc.edu [PDF] 
JI Barzilay, BR Davis, JA Cutler, SL Pressel … - Archives of internal …, 2006 - archinte.highwire.org
Background Elevated blood glucose levels are reported with thiazide-type diuretic treatment
of hypertension. The significance of this finding is uncertain. Our objectives were to compare
the effect of first-step antihypertensive drug therapy with thiazide-type diuretic, calcium- ...
Cited by 52 - Related articles - BL Direct - All 9 versions

Telmisartan downregulates angiotensin II type 1 receptor through activation of …

- oxfordjournals.org
I Imayama, T Ichiki, K Inanaga, H … - Cardiovascular …, 2006 - cardiovascres.oxfordjournals.org
Results: Telmisartan decreased the expression of AT1R at the mRNA and protein levels in a
dose- and time-dependent manner. Decreased AT1R promoter activity with unchanged mRNA
stability suggested that telmisartan suppressed AT1R gene expression at the ...
Cited by 26 - Related articles - All 6 versions

The chronic kidney disease epidemic: stepping back and looking forward

- asnjournals.org
B Kiberd - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol
Estimating the prevalence of chronic kidney disease (CKD) is no simple task. The overall prevalence
is relatively low but may be higher in select populations that are not accessible to surveys
(eg, certain ethnic groups, the sick or elderly). Moreover, the tests that define CKD lack ...
Cited by 22 - Related articles - BL Direct - All 6 versions

Insulin resistance, inflammatory biomarkers, and adipokines in patients with …

- asnjournals.org
SG de Vinuesa, M Goicoechea, J Kanter, M … - Journal of the American …, 2006 - Am Soc Nephrol
Patients with chronic kidney disease (CKD) present a high prevalence of insulin resistance
(IR). Some studies suggest that angiotensin II may influence some cellular pathways that contribute
to the pathogenesis of IR and stimulate the release of proinflammatory cytokines. Fifty-two ...
Cited by 24 - Related articles - All 6 versions

Renin-angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and …

- nursing2008.com
R Sarzani, F Salvi, P Dessi-Fulgheri, A … - Journal of …, 2008 - journals.lww.com
The obesity pandemic is closely related to hypertension and metabolic syndrome. Visceral adipose
tissue plays a key role in the metabolic and cardiovascular complications of being
overweight. The pathophysiological link between visceral adiposity and cardiometabolic ...
Cited by 21 - Related articles - All 5 versions

The role of renin–angiotensin system inhibition in the treatment of hypertension in …


… , DP Mikhailidis, VG Athyros, AI Kakafika … - Expert Opinion on …, 2007 - Informa Pharma Science
The metabolic syndrome (MetS) is a strong predictor of cardiovascular morbidity and
mortality, as well as new Type 2 diabetes. MetS consists of visceral obesity, elevated blood
pressure, impaired glucose metabolism, atherogenic dyslipidaemia (elevated ...
Cited by 17 - Related articles - BL Direct - All 4 versions

Metabolic syndrome: treatment of hypertensive patients

- smajournalonline.org
ZH Israili, B Lyoussi, R Hernandez- … - American journal of …, 2007 - journals.lww.com
Metabolic syndrome (MetSyndr), a constellation of abnormalities [obesity, glucose
intolerance, insulin resistance (IR), dyslipidemia (low HDL-cholesterol, high LDL-cholesterol
and triglycerides (TG)], and elevated blood pressure (BP)], increases the risk of ...
Cited by 17 - Related articles - BL Direct - All 7 versions


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