- ►biologists.org A Leask, DJ Abraham - Journal of cell science, 2006 - jcs.biologists.org The CCN family is a group of six secreted proteins that specifically associate
with the extracellular matrix. Structurally, CCN proteins are modular,
containing up to four distinct functional domains. CCN family members are ... Cited by 119 - Related articles - BL Direct - All 4 versions
- ►uu.nl [PDF] TQ Nguyen, R Goldschmeding - Pharmaceutical Research, 2008 - Springer Received December 30, 2007; accepted January 28, 2008; published online
Ferbruary 12, 2008 Abstract. Renal fibrosis is the major determinant in
progression of kidney disease and results from an inappropriate response to ... Cited by 16 - Related articles - All 5 versions
TQ Nguyen, P Roestenberg, FA van … - J Am Soc Nephrol, 2008 - Am Soc Nephrol ABSTRACT In diabetic nephropathy, connective tissue growth factor (CTGF) is
upregulated and bone morpho- genetic protein 7 (BMP-7) is downregulated. CTGF is
known to inhibit BMP-4, but similar cross-talk between BMP-7 and CTGF has ... Cited by 13 - Related articles - All 7 versions
CR Ban, SM Twigg - Vascular Health and Risk Management, 2008 - pubmedcentral.nih.gov Diabetes mellitus is characterized by a lack of insulin causing elevated blood
glucose, often with associated insulin resistance. Over time, especially in
genetically susceptible individuals, such chronic hyperglycemia can cause ... Cited by 7 - Related articles - All 8 versions
BA Brooks, B Franjic, CR Ban, K Swaraj, DK … - Diabetes Obes Metab, 2007 - interscience.wiley.com Aim: Diabetic cardiomyopathy is an increasingly recognized entity. The
pathogenic factors that may contribute to its development, especially the
earliest changes of diastolic dysfunction (DD), have not been clearly ... Cited by 7 - Related articles - All 2 versions
Z Tu, Y Shi, J Wang, J Bao, H Bu - Nephrology, 2007 - interscience.wiley.com Methods: Kidney transplantation was performed from Lewis to Fisher 344
allogeneic rat strain, and kidney grafts were harvested at the eighth, 12th and
16th week. The morphological changes were studied, and collagen deposition ... Cited by 5 - Related articles - BL Direct - All 3 versions
- Free from Publisher TQ Nguyen, L Tarnow, A Jorsal, N Oliver, P … - Diabetes care, 2008 - Am Diabetes Assoc RESULTS—Plasma CTGF was higher in patients with nephropathy than in patients
with normoalbuminuria (median 381 [interquartile range 270–630] vs. 235
[168–353] pmol/l). In patients with nephropathy, elevated plasma CTGF was ... Cited by 5 - Related articles - BL Direct - All 7 versions
LL Lv, BC Liu - Proteomic, Clin Appl, 2008 - interscience.wiley.com Chronic kidney disease (CKD) that affects about 10% of the adult population has
been shown as a worldwide public health problem in recent years. Both basic and
clinical investigations have identified complex disease-associated protein ... Cited by 4 - Related articles
A Daniels, M van Bilsen, R Goldschmeding, … - Acta Physiol (Oxf), 2009 - interscience.wiley.com Cardiac fibrosis is a major pathogenic factor in a variety of cardiovascular
diseases and refers to an excessive deposition of extracellular matrix
components in the heart, which leads to cardiac dysfunction and eventually ... Cited by 2 - Related articles - All 3 versions
