- ►oxfordjournals.org AL Fitzpatrick, RA Kronmal, JP Gardner, BM … - American Journal of …, 2007 - Oxford Univ Press The telomere length of replicating somatic cells is inversely correlated with age and has been
reported to be associated cross-sectionally with cardiovascular disease (CVD). Leukocyte telomere
length, as expressed by mean terminal restriction fragment (TRF) length, was measured ... Cited by 97 - Related articles - BL Direct - All 10 versions
- ►ahajournals.org JJ Fuster, V Andres - Circulation research, 2006 - Am Heart Assoc Accumulation of cellular damage with advancing age leads to atherothrombosis and associated
cardiovascular disease. Ageing is also characterized by shortening of the DNA component of
telomeres, the specialized genetic segments located at the end of eukaryotic ... Cited by 52 - Related articles - All 11 versions
- ►twinsuk.ac.uk [PDF] LF Cherkas, JL Hunkin, BS Kato, JB Richards, … - Archives of internal …, 2008 - Am Med Assoc Results Leukocyte telomere length was positively associated with increasing physical activity
level in leisure time (P < .001); this association remained significant after adjustment for age,
sex, body mass index, smoking, socioeconomic status, and physical activity at work. The ... Cited by 50 - Related articles - BL Direct - All 10 versions
D Ornish, J Lin, J Daubenmier, G Weidner, E Epel, C … - Lancet Oncology, 2008 - Elsevier Telomeres are protective DNA–protein complexes at the end of linear chromosomes that promote
chromosomal stability. Telomere shortness in human beings is emerging as a prognostic marker
of disease risk, progression, and premature mortality in many types of cancer, including ... Cited by 20 - Related articles - All 23 versions
NJ Samani, P van der Harst - British Medical Journal, 2008 - heart.bmj.com At a population level, several environmental, lifestyle and genetic risk factors contribute to the
development of coronary artery disease (CAD) and heart failure. However, at an individual
level, both susceptibility to, and the age of onset of, these conditions vary considerably ... Cited by 20 - Related articles - BL Direct - All 4 versions
… , M Balasubramanyam, R Ravikumar, R Deepa, V … - Atherosclerosis, 2007 - Elsevier Subjects with impaired glucose tolerance (IGT) (n = 30), non-diabetic control subjects (n =
30), Type 2 diabetic patients without (n = 30) and with atherosclerotic plaques (n = 30) were selected
from the Chennai Urban Rural Epidemiology Study (CURES), an ongoing ... Cited by 16 - Related articles - All 32 versions
MJ Sampson, DA Hughes - Diabetologia, 2006 - Springer Abstract Telomeres are the repeat DNA sequences at the end of chromosomes necessary for
successful DNA replication and chromosomal integrity. Telomeres shorten at cell division at a
rate determined by oxidative DNA damage, and cells are triggered into replicative ... Cited by 14 - Related articles - BL Direct - All 3 versions
- ►nursing2008.com PM Nilsson, E Lurbe, S Laurent - Journal of Hypertension, 2008 - journals.lww.com Early vascular ageing is common in patients with hypertension and increased burden of cardiovascular
risk factors, often influenced by chronic inflammation. One aspect of this vascular ageing is arterial
stiffening, as measured by increased pulse wave velocity or augmentation index and ... Cited by 16 - Related articles - BL Direct - All 6 versions
K Nordfjäll, P Osterman, O Melander, P Nilsson, G … - … and Biophysical Research …, 2007 - Elsevier Regulation of the telomerase catalytic subunit, hTERT, is a complex process accomplished on
many levels. Transcription of the hTERT gene has been widely studied but less is known about
the implication of genetic variations. Recently, a functional T to C transition polymorphism ... Cited by 12 - Related articles - All 6 versions
R Abe, S Yamagishi - Current pharmaceutical design, 2008 - ingentaconnect.com Abstract: Recent clinical studies have reported an increased risk for various types of cancers
in patients with diabetes. Diabetes is char- acterized by increased oxidative stress
conditions. Hyperglycemia induces oxidative stress generation in a variety of cells via ... Cited by 10 - Related articles - BL Direct - All 4 versions
