AD Roses, AM Saunders, Y Huang, J Strum, KH … - The pharmacogenomics …, 2006 - nature.com Safety and efficacy pharmacogenetics can be applied successfully to the drug discovery and
development pipeline at multiple phases. We review drug-target screening using high throughput
SNP associations with complex diseases testing more than 1 800 candidate targets with ... Cited by 35 - Related articles - BL Direct - All 4 versions
GJ Biessels, IJ Deary, CM Ryan - Lancet Neurology, 2008 - Elsevier Diabetes mellitus is associated with cognitive dysfunction and abnormalities that can be seen
with brain imaging. Recent studies provide important new insights into the nature and severity
of these cerebral complications that help to explain why some patients with diabetes have ... Cited by 25 - Related articles - All 20 versions
- ►ahajournals.org JV Bowler, PB Gorelick - Stroke, 2007 - Am Heart Assoc Vascular cognitive impairment is common and represents a spectrum of cognitive dysfunction
associated with stroke and cardiovascular risk factors which may be slight, moderate or
severe. 1 Recently and as a major advance, the National Institute of Neurological ... Cited by 18 - Related articles - All 8 versions
E Van den Berg, RPC Kessels, LJ Kappelle, EHF de … - Drugs Today, 2006 - journals.prous.com Type 2 diabetes is a common metabolic disease with a rising global prevalence. It is associated
with slowly progressive end-organ damage in the eyes and kidneys, but also in the brain. The
latter complication is often referred to as “diabetic encephalopathy” and is characterized ... Cited by 13 - Related articles - All 9 versions
SR Colberg, CT Somma, SR Sechrist - Journal of the American Medical …, 2008 - Elsevier The presence of diabetes had a negative impact on at least one measure of cognitive function
(MMSE), even though such function was fairly intact in most subjects (29.3 ± 0.1 Con, 28.7 ±
0.2 DM, P < .05). MMSE scores were significantly inversely associated with fasting insulin ... Cited by 10 - Related articles - All 15 versions
- ►oxfordjournals.org N Coley, S Andrieu, V Gardette, S Gillette- … - Epidemiologic …, 2008 - Soc Epidemiolc Res The prevention of neurodegenerative dementias, such as Alzheimer disease, is a growing public
health concern, because of a lack of effective curative treatment options and a rising global
prevalence. Various potential risk or preventive factors have been suggested by ... Cited by 9 - Related articles - All 5 versions
MWJ Strachan, JF Price, BM Frier - British Medical Journal, 2008 - bmj.com Early data that linked type 2 diabetes with cognitive impairment came from cross sectional cohort
studies that were generally of poor methodological quality. 4 However, a recent systematic review
of prospective observational studies identified 25 articles that assessed the link between ... Cited by 8 - Related articles - BL Direct - All 3 versions
AS Slingerland, W Hurkx, K Noordam, SE … - Diabetic …, 2008 - interscience.wiley.com Methods The patient had a low birth weight and was found to have diabetes at the age of 2
days. The patient was treated with insulin from diagnosis. The child also had marked developmental
delay so that his average functional age was 2.5 years when he was 12 years old. A ... Cited by 8 - Related articles - BL Direct - All 5 versions
A Cobitz, A Zambanini, M Sowell, M Heise … - … and drug safety, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 7 - Related articles - All 4 versions
RS McIntyre, JK Soczynska, GF Lewis, … - Expert Opin. …, 2006 - Informa Pharma Science The objective of this paper is to synthesise extant studies describing the neurotherapeutic effects
of antidiabetic agents in neuropsychiatric disorders. The authors conducted a MedLine search
of all English-language articles published between 1966 and March 2006. The search ... Cited by 7 - Related articles - BL Direct - All 5 versions
