GS Eisenbarth, J Jeffrey - Arquivos Brasileiros de Endocrinologia & …, 2008 - SciELO Brasil Keywords: type 1 diabetes; Anti-islet autoimmunity; Autoantibodies; HlA, genetic ... RESuMO
A História do Diabetes Melito Tipo 1. Atualmente o desenvolvimento do diabetes melito tipo
1 A( imune mediado) pode ser predito através da determinação de quatro ... Cited by 35 - Related articles - View as HTML - All 6 versions
JS Skyler - Clinical Pharmacology & Therapeutics, 2007 - nature.com Type 1 diabetes mellitus (T1D) arises from selective immunologically mediated destruction of
the insulin-producing -cells in the pancreatic islets of Langerhans with consequent insulin
deficiency. 1, 2 This occurs in genetically susceptible individuals and is a ... Cited by 33 - Related articles - All 4 versions
- ►diabetesjournals.org JM Sosenko, JP Palmer, CJ Greenbaum, J Mahon, … - Diabetes care, 2007 - Am Diabetes Assoc RESULTS—ROC areas under the curve (ROCAUCs) for both the AUC glucose (0.73 ± 0.02)
and an OGTT prediction index (0.78 ± 0.02) were higher (P < 0.001) than those for the fasting
(0.53 ± 0.02) and 2-h glucose (0.66 ± 0.02). ROCAUCs for the 60- and 90-min glucose ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org E Akirav, JA Kushner, KC Herold - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The loss of β-cells that characterizes type 1 diabetes reflects the net effects of destruction
and regeneration. These processes have been examined in the nonobese diabetic (NOD)
mouse; uncertainty remains about β-cell dynamics in humans. Islet inflammation ... Cited by 10 - Related articles - All 4 versions
DJ Klinke… - PLoS ONE, 2008 - pubmedcentral.nih.gov The histopathology results identifying insulin containing islets in patients younger than 20 years
of age were extracted from three different studies. The results for 105 patients were stratified
by duration of diabetic symptoms and age at onset. Linear regression and a ... Cited by 5 - Related articles - All 4 versions
- ►diabetesjournals.org JM Sosenko, JP Krischer, JP Palmer, J Mahon, C … - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—A risk score based on a model including log-BMI, age, log-fasting C-peptide, and
postchallenge glucose and C-peptide sums from 2-h oral glucose tolerance tests (OGTTs) was
derived from the development sample. The baseline risk score strongly predicted type 1 ... Cited by 6 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org V Butty, C Campbell, D Mathis, C Benoist - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The unfolding of type 1 diabetes involves a number of steps: defective immunological
tolerance, priming of anti-islet autoimmunity, and destruction of insulin-producing β-cells. A number
of genetic loci contribute to susceptibility to type 1 diabetes, but it is unclear which stages ... Cited by 4 - Related articles - All 5 versions
PE Harris, C Ferrara, P Barba, T Polito, M Freeby, A … - Journal of Molecular …, 2008 - Springer Page 1. REVIEW VMAT2 gene expression and function as it applies to imaging β-cell
mass Paul E. Harris & Caterina Ferrara & Pasquale Barba & Teresa Polito & Matthew
Freeby & Antonella Maffei Received: 6 April 2007 /Revised ... Cited by 4 - Related articles - BL Direct - All 2 versions
J Sherr, J Sosenko, JS Skyler, KC Herold - Nature clinical practice. …, 2008 - ncbi.nlm.nih.gov 1: Nat Clin Pract Endocrinol Metab. 2008 Jun;4(6):334-43. Epub 2008 Apr 29. Prevention of
type 1 diabetes: the time has come. Sherr J, Sosenko J, Skyler JS, Herold KC. Department of
Pediatrics, Yale University School of Medicine, New Haven, CT, USA. ... Cited by 6 - Related articles - BL Direct - All 3 versions
JM Sosenko, JP Palmer, L Rafkin-Mervis, JP … - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—Glucose levels increased at 90 (P = 0.006) and 120 min (P < 0.001) from the initial
diabetic OGTT to the confirmatory diabetic OGTT (mean ± SD interval 5.5 ± 2.8 weeks). Peak
C-peptide levels fell substantially between the OGTTs (median change −14.3%, P < ... Cited by 5 - Related articles - All 3 versions
