P Xu, D Cuthbertson, C Greenbaum, JP Palmer, JP … - Diabetes Care, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Subjects (n = 186) who had a projected 25–50% risk
for diabetes and subjects (n = 170) who had a projected >50% risk for type 1 diabetes in 5 years
were followed until clinical diabetes onset or the end of the study as part of the Diabetes ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►pubget.com [PDF] P Achenbach, K Warncke, J Reiter, AJK Williams, AG … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Combinations of autoantibody character- istics, including antibody
number, titre, subclass and epitope have been shown to stratify type 1 diabetes risk in islet
autoantibody-positive relatives. The aim of this study was to determine whether ... Cited by 15 - Related articles - BL Direct - All 6 versions
P Dejkhamron, RK Menon, MA Sperling - INDIAN JOURNAL OF MEDICAL …, 2007 - medind.nic.in Diabetes mellitus (DM) is a metabolic disease characterized by absolute or relative insulin
deficiency. Absolute deficiency of insulin most commonly results from an autoimmune destruction
of insulin producing cells in the pancreas and in general, the term Type 1 DM (T1DM) is ... Cited by 10 - Related articles - View as HTML - BL Direct - All 4 versions
- ►diabetesjournals.org PJ Bingley, JL Mahon, EAM Gale - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—The overall cumulative risk of diabetes within 5 years was 54.1% (95% CI
46.0–62.3). Multivariate analysis confirmed that baseline first-phase insulin response (FPIR)
quartile (P < 0.0001), number of additional antibody markers (P < 0.0001), and 120-min ... Cited by 9 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org JM Sosenko, JP Krischer, JP Palmer, J Mahon, C … - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—A risk score based on a model including log-BMI, age, log-fasting C-peptide, and
postchallenge glucose and C-peptide sums from 2-h oral glucose tolerance tests (OGTTs) was
derived from the development sample. The baseline risk score strongly predicted type 1 ... Cited by 6 - Related articles - BL Direct - All 5 versions
- ►nursing2008.com TTL Pang, P Narendran - Diabetic Medicine, 2008 - pt.wkhealth.com Type 1 diabetes is recognised to include an element of insulin resistance. Insulin resistance
is an independent risk factor for the development of macro- and microvascular complications
of Type 1 diabetes and may also contribute to the development of the disease. This ... Cited by 4 - Related articles - All 5 versions
NR Rose - Autoimmunity, 2008 - informahealthcare.com Increased emphasis has been placed in recent years on predictive biomarkers to foretell the
onset or future course of disease. In autoimmune diseases, autoantibodies have proven to be
valuable biomarkers because of their technical sensitivity, specificity, and stability during ... Cited by 4 - Related articles - All 6 versions
NR ROSE - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2007 - interscience.wiley.com Abstract : Biomarkers, represented by genetically determined traits or biologic changes predictive
of disease onset or outcome, are increasingly employed by academic and industrial
investigators. They can identify unusually susceptible populations or individuals, facilitate ... Cited by 1 - Related articles - BL Direct - All 4 versions
JL Mahon, JM Sosenko, L Rafkin-Mervis, H … - Pediatric …, 2009 - ingentaconnect.com Mahon JL, Sosenko JM, Rafkin-Mervis L, Krause-Steinrauf H, Lachin JM, Thompson C, Bingley
PJ, Bonifacio E, Palmer JP, Eisenbarth GS, Wolfsdorf J, Skyler JS, for the TrialNet Natural History
Committee and Type 1 Diabetes TrialNet Study Group. The TrialNet Natural History Study ... Cited by 1 - Related articles - All 2 versions
M Falchi, SG Wilson, D Paximadas, R Swaminathan, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Genome-wide variance component linkage analysis using 2,231 genetic markers
identified a highly significant quantitative trait locus for BCF on chromosome 10p15 (logarithm
of odds [LOD] 6.2, P = 0.0001), a region recently shown to contain a functional variant for ... Cited by 1 - Related articles - BL Direct - All 7 versions
