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Scholar Results 1 - 10 of about 22 citing Konoshita: Tissue gene expression of renin-angiotensin system in human type 2 diabetic nephropathy. (0.14 sec) 

Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury

- amjpathol.org
DW Wong, GY Oudit, H Reich, Z Kassiri, J … - American Journal of Pathology, 2007 - ASIP
Activation of the renin-angiotensin system (RAS) and the generation of
angiotensin (Ang) II play an important role in the pathogenesis of diabetic
nephropathy and blockade of the RAS in both experimental and clinical ...
Cited by 34 - Related articles - BL Direct - All 8 versions

[PDF] Emerging role of ACE2 in physiology and disease Emerging role of ACE2 in physiology and …


I Hamming, ME Cooper, BL Haagmans, NM … - Journal of Pathology, 2007 - dissertations.ub.rug.nl
The renin-angiotensin-aldosterone system (RAAS) is a key regulator of systemic
blood pressure and renal function and a key player in renal and cardiovascular
disease. However, its (patho)physiological roles and its architecture are ...
Cited by 33 - Related articles - View as HTML - BL Direct - All 5 versions

Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal …

- endojournals.org
S Wakahara, T Konoshita, S Mizuno, M … - Endocrinology, 2007 - Endocrine Soc
Angiotensin-converting enzyme (ACE) 2, a newly emerging component of the
renin-angiotensin system, is presumed to be a counterregulator against ACE in
generating and degrading angiotensin II. It remains to be elucidated how ...
Cited by 20 - Related articles - BL Direct - All 6 versions

ACE2: A New Target for Prevention of Diabetic Nephropathy?


JR Ingelfinger - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol
Abundant, well-accepted evidence demonstrates a complete tissue
renin-angiotensin system (RAS) within the kidney that plays many roles in the
control of the intrarenal vasculature, as well in the control of glomerular ...
Cited by 11 - Related articles - BL Direct - All 5 versions

The emerging role of angiotensin-converting enzyme-2 in the kidney

- turkiyeklinikleri.com [PDF] 
KD Burns - Current opinion in nephrology and hypertension, 2007 - journals.lww.com
Purpose of review The intrarenal renin–angiotensin system contributes to the
progression of chronic kidney disease. Angiotensin- converting enzyme-2 is a
recently identified protein that is highly expressed in the kidney and ...
Cited by 9 - Related articles - BL Direct - All 10 versions

Differential regulation of renal angiotensin-converting enzyme (ACE) and ACE2 during ACE …

- physoc.org
I Hamming, H van Goor, AJ Turner, CA … - Experimental Physiology, 2008 - expphysiol.highwire.org
Angiotensin-converting enzyme (ACE) 2 is thought to counterbalance ACE by
breakdown of angiotensin (Ang) II and formation of Ang(1–7). Both enzymes are
highly expressed in the kidney, but reports on their regulation differ. To ...
Cited by 8 - Related articles - BL Direct - All 8 versions

Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy


G Wang, FMM Lai, KB Lai, KM Chow, CHB … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis The interplay of ACE and type 2 ACE (ACE2) has been
recognised as playing an important role in the tissue renin–angiotensin system
within the kidney. In the present study, we measured urinary mRNA ...
Cited by 6 - Related articles - BL Direct - All 2 versions

Angiotensin-converting enzyme 2 and the kidney

- physoc.org
MJ Soler, J Wysocki, D Batlle - Experimental Physiology, 2008 - Physiological Soc
Angiotensin-converting enzyme (ACE) 2 is a homologue of ACE with enzymatic
activity that seems to counterbalance the angiotensin II-promoting effect of
ACE. While ACE promotes angiotensin (Ang) II formation from Ang I, ACE2 ...
Cited by 5 - Related articles - BL Direct - All 10 versions

Urinary albumin excretion is a risk factor for diabetes mellitus in men, independently of …


JM Halimi, F Bonnet, C Lange, B Balkau, J … - Journal of hypertension, 2008 - journals.lww.com
Background: Elevated urinary albumin excretion (UAE) is more frequent in
patients with the metabolic syndrome or insulin resistance. Whether UAE predicts
the development of diabetes mellitus, independently of the presence or the ...
Cited by 3 - Related articles - All 4 versions

Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and …


HN Reich, GY Oudit, JM Penninger, JW … - Kidney International, 2008 - nature.com
Angiotensin converting enzyme (ACE) generates angiotensin II from angiotensin I,
which plays a critical role in the pathophysiology of diabetic nephropathy.
However, ACE2 generates angiotensin 1–7, which may protect the kidney by ...
Cited by 3 - Related articles - All 3 versions


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