- ►amjpathol.org DW Wong, GY Oudit, H Reich, Z Kassiri, J … - American Journal of Pathology, 2007 - ASIP Activation of the renin-angiotensin system (RAS) and the generation of
angiotensin (Ang) II play an important role in the pathogenesis of diabetic
nephropathy and blockade of the RAS in both experimental and clinical ... Cited by 34 - Related articles - BL Direct - All 8 versions
I Hamming, ME Cooper, BL Haagmans, NM … - Journal of Pathology, 2007 - dissertations.ub.rug.nl The renin-angiotensin-aldosterone system (RAAS) is a key regulator of systemic
blood pressure and renal function and a key player in renal and cardiovascular
disease. However, its (patho)physiological roles and its architecture are ... Cited by 33 - Related articles - View as HTML - BL Direct - All 5 versions
- ►endojournals.org S Wakahara, T Konoshita, S Mizuno, M … - Endocrinology, 2007 - Endocrine Soc Angiotensin-converting enzyme (ACE) 2, a newly emerging component of the
renin-angiotensin system, is presumed to be a counterregulator against ACE in
generating and degrading angiotensin II. It remains to be elucidated how ... Cited by 20 - Related articles - BL Direct - All 6 versions
JR Ingelfinger - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Abundant, well-accepted evidence demonstrates a complete tissue
renin-angiotensin system (RAS) within the kidney that plays many roles in the
control of the intrarenal vasculature, as well in the control of glomerular ... Cited by 11 - Related articles - BL Direct - All 5 versions
- ►turkiyeklinikleri.com [PDF] KD Burns - Current opinion in nephrology and hypertension, 2007 - journals.lww.com Purpose of review The intrarenal renin–angiotensin system contributes to the
progression of chronic kidney disease. Angiotensin- converting enzyme-2 is a
recently identified protein that is highly expressed in the kidney and ... Cited by 9 - Related articles - BL Direct - All 10 versions
- ►physoc.org I Hamming, H van Goor, AJ Turner, CA … - Experimental Physiology, 2008 - expphysiol.highwire.org Angiotensin-converting enzyme (ACE) 2 is thought to counterbalance ACE by
breakdown of angiotensin (Ang) II and formation of Ang(1–7). Both enzymes are
highly expressed in the kidney, but reports on their regulation differ. To ... Cited by 8 - Related articles - BL Direct - All 8 versions
G Wang, FMM Lai, KB Lai, KM Chow, CHB … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis The interplay of ACE and type 2 ACE (ACE2) has been
recognised as playing an important role in the tissue renin–angiotensin system
within the kidney. In the present study, we measured urinary mRNA ... Cited by 6 - Related articles - BL Direct - All 2 versions
- ►physoc.org MJ Soler, J Wysocki, D Batlle - Experimental Physiology, 2008 - Physiological Soc Angiotensin-converting enzyme (ACE) 2 is a homologue of ACE with enzymatic
activity that seems to counterbalance the angiotensin II-promoting effect of
ACE. While ACE promotes angiotensin (Ang) II formation from Ang I, ACE2 ... Cited by 5 - Related articles - BL Direct - All 10 versions
JM Halimi, F Bonnet, C Lange, B Balkau, J … - Journal of hypertension, 2008 - journals.lww.com Background: Elevated urinary albumin excretion (UAE) is more frequent in
patients with the metabolic syndrome or insulin resistance. Whether UAE predicts
the development of diabetes mellitus, independently of the presence or the ... Cited by 3 - Related articles - All 4 versions
HN Reich, GY Oudit, JM Penninger, JW … - Kidney International, 2008 - nature.com Angiotensin converting enzyme (ACE) generates angiotensin II from angiotensin I,
which plays a critical role in the pathophysiology of diabetic nephropathy.
However, ACE2 generates angiotensin 1–7, which may protect the kidney by ... Cited by 3 - Related articles - All 3 versions