- ►onmedic.net [PDF] M Laclaustra, D Corella, JM Ordovas - Nutrition, Metabolism and Cardiovascular Diseases, 2007 - Elsevier Several pathophysiological explanations for the metabolic syndrome have been
proposed involving insulin resistance, chronic inflammation and ectopic fat
accumulation following adipose tissue saturation. However, current concepts ... Cited by 38 - Related articles - All 25 versions
- ►ciberobn.info [PDF] J Lopez-Miranda, C Williams, D Lairon - British Journal of Nutrition, 2007 - Cambridge Univ Press Most of diurnal time is spent in a postprandial state due to successive meal
intakes during the day. As long as the meals contain enough fat, a transient
increase in triacylglycerolaemia and a change in lipoprotein pattern ... Cited by 30 - Related articles - BL Direct - All 10 versions
- ►mdl-labs.com [PDF] MTR Subbiah - Translational Research, 2007 - Elsevier The Human Genome Project and subsequent identification of single nucleotide
polymorphisms (SNPs) within populations has played a major role in predicting
individual response to drugs (pharmacogenetics) leading to the concept of ... Cited by 23 - Related articles - All 15 versions
- ►gendermedjournal.com [PDF] JM Ordovas - Gender Medicine, 2007 - Elsevier Results: Evidence from some key factors in lipid metabolism (apolipoprotein E
[APOE])and obesity (perilipin [PLIN]) indicates that the interplay between
genes, gender, and environmental factors modulates disease susceptibility. ... Cited by 19 - Related articles - All 9 versions
J Kaput - Current Opinion in Biotechnology, 2008 - Elsevier Current nutritional and genetic epidemiological methods yield 'risk factors' on
the basis of population studies. Risk factors, however, are statistical
estimates of the percentage reduction in disease in the population if the ... Cited by 16 - Related articles - All 4 versions
ES Tai, JM Ordovas - Current opinion in lipidology, 2007 - journals.lww.com Recent findings: The mechanisms that control the storage and release of
triacylglycerides in lipid droplets are complex and poorly understood; yet, they
are likely to be crucial to the understanding of the regulation of body ... Cited by 13 - Related articles - BL Direct - All 8 versions
- ►jbc.org J Kovsan, R Ben-Romano, SC Souza, AS … - Journal of Biological Chemistry, 2007 - ASBMB A decrease in the lipid droplet-associated protein perilipin may constitute a
mechanism for enhanced adipocyte lipolysis under nonstimulated (basal)
conditions, and increased basal lipolysis has been linked to whole body ... Cited by 12 - Related articles - All 5 versions
- ►nih.gov JM Ordovas, J Shen - Journal of periodontology, 2008 - Am Acad Periodontology There is an intrinsic complexity in the pathogenesis of common diseases. The
concept of gene–environment interaction is receiving support from emerging
evidence coming primarily from studies involving diet and cardiovascular ... Cited by 7 - Related articles - All 11 versions
GVZ Dedoussis, AC Kaliora, DB … - The Review of Diabetic Studies, 2007 - pubmedcentral.nih.gov Diabetes mellitus is widely recognized as one of the leading causes of death and
disability. While insulin insensitivity is an early phenomenon partly related to
obesity, pancreatic β-cell function declines gradually over time even ... Cited by 8 - Related articles - All 4 versions
- ►ciberobn.es [PDF] J López-Miranda, P Pérez-Martínez, C Marin, … - Journal of Molecular Medicine, 2007 - Springer Abstract Both insulin resistance and dyslipidaemia are determined by genetic and
environmental factors. Depending on their expression and their function, gene
variants may influence either insulin action or dyslipidaemia. The purpose ... Cited by 4 - Related articles - BL Direct - All 6 versions
