- ►diabetesjournals.org VR Drel, N Mashtalir, O Ilnytska, J Shin, F Li, VV … - Diabetes, 2006 - Am Diabetes Assoc Whereas functional, metabolic, neurotrophic, and morphological abnormalities of peripheral
diabetic neuropathy (PDN) have been extensively explored in streptozotocin-induced diabetic
rats and mice (models of type 1 diabetes), insufficient information is available on ... Cited by 31 - Related articles - BL Direct - All 7 versions
PJ Oates - Current drug targets, 2008 - ingentaconnect.com Abstract: Aldose reductase (AR) enzymatically transforms cytosolic glucose into sorbitol, a molecule
that poorly pene- trates cell membranes and is sometimes slowly metabolized. Hyperglycemia
can cause intracellular accumulation of sorbi- tol and its metabolite, fructose, which can ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►adisonline.com [PDF] MS Chong, J Hester - Drugs, 2007 - ingentaconnect.com Diabetic painful neuropathy (DPN) is one of the most common causes of Abstract neuropathic
pain. The management of DPN consists of excluding other causes of painful peripheral
neuropathy, maximising diabetic control and using medications to alleviate pain. The ... Cited by 22 - Related articles - BL Direct - All 7 versions
- ►prsjournal.com AJM Boulton - Current Opinion in Endocrinology, Diabetes and …, 2007 - journals.lww.com Recent findings: Classification of the diabetic neuropathies needs modifying to include the recently
described 'prediabetic neuropathy' or 'neuropathy of impaired glucose tolerance'. There is increasing
evidence to support the use of minimally invasive skin biopsies for evaluating small fibre ... Cited by 13 - Related articles - BL Direct - All 6 versions
T Varkonyi, P Kempler - Diabetes, Obesity & Metabolism, 2008 - pt.wkhealth.com Current therapeutic possibilities can be divided into two groups: the pathogenetically oriented
and the symptomatic therapy. One of the most important component of etiology-based treatment
is the stabilization of glycemic control. Based on efficacy and safety data benfotiamine ... Cited by 11 - Related articles - BL Direct - All 4 versions
Y Ido - Antioxidants & Redox Signaling, 2007 - liebertonline.com C HEMICAL REACTIONS involving movement of electrons are called redox reactions (reduction
and oxidation). This review will describe characteristics of redox abnormali- ties observed in
diabetes. Diabetes affects a number of tissues and organs including liver, micro- and ... Cited by 11 - Related articles - BL Direct - All 5 versions
- ►nih.gov CA Gleissner, E Galkina, JL Nadler, K Ley - Drug Discovery Today: Disease …, 2007 - Elsevier Diabetes mellitus is one of the major risk factors for atherosclerosis, an inflammatory disease
of the arterial wall, in which leukocytes and oxidized lipoproteins accumulate leading to formation
of fatty streaks and atherosclerotic plaques [1]. Atherosclerosis accounts for more than ... Cited by 7 - Related articles - All 3 versions
B Bulic, M Pickhardt, I Khlistunova, J … - ANGEWANDTE …, 2007 - mpasmb-hamburg.mpg.de The two histopathological hallmarks that characterize Alz- heimer s disease (AD) are the extracellular
amyloid plaques that are formed by b-amyloid fragments of the amyloid precursor protein
(APP), and intracellular neurofibrillary tangles and neuropil threads, which consist of the ... Cited by 7 - Related articles - View as HTML - BL Direct - All 4 versions
H Yokoyama, Y Yokota, J Tada, S Kanno - Diabetic Medicine, 2007 - pt.wkhealth.com Methods: In 294 patients with Type 2 diabetes, neuropathy was assessed by four
components: the presence of neuropathic symptoms, the absence of ankle tendon reflexes, perception
of vibration scores and heart rate variation. We measured intima-media thickness (IMT) of ... Cited by 6 - Related articles - BL Direct - All 6 versions
BC Cumbie, KL Hermayer - Vascular Health and Risk …, 2007 - pubmedcentral.nih.gov Microvascular complications characterized by retinopathy, nephropathy, and neuropathy are
highly prevalent among diabetics. Glycemic control has long been the mainstay for preventing
progression of these complications; however, such control is not easily achieved. ... Cited by 5 - Related articles - BL Direct - All 8 versions
