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β-Cell Mass and Type 1 Diabetes

- diabetesjournals.org
E Akirav, JA Kushner, KC Herold - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— The loss of β-cells that characterizes type 1 diabetes reflects the
net effects of destruction and regeneration. These processes have been examined
in the nonobese diabetic (NOD) mouse; uncertainty remains about β-cell ...
Cited by 10 - Related articles - All 4 versions

Prevention of type 1 diabetes: the time has come.


J Sherr, J Sosenko, JS Skyler, KC Herold - Nature clinical practice. Endocrinology & metabolism, 2008 - ncbi.nlm.nih.gov
1: Nat Clin Pract Endocrinol Metab. 2008 Jun;4(6):334-43. Epub 2008 Apr
29. Prevention of type 1 diabetes: the time has come. Sherr ...
Cited by 6 - Related articles - BL Direct - All 3 versions

Type 1 diabetes: chronic progressive autoimmune disease.


L Zhang, R Gianani, M Nakayama, E Liu, M … - Novartis Foundation symposium, 2008 - ncbi.nlm.nih.gov
A wealth of data in animal models indicates that type 1A diabetes results from T
cell-mediated specific destruction of islet beta cells. There is evidence for
the NOD mouse model that insulin is the primary autoantigen and a specific ...
Cited by 1 - Related articles - All 2 versions

Early Metabolic Markers of Islet Allograft Dysfunction


DA Baidal, RN Faradji, S Messinger, T Froud, … - Transplantation, 2009 - journals.lww.com
Islet transplantation (IT) can restore normoglycemia and improve the quality of
life of patients with unstable type 1 diabetes mellitus (T1DM) (1). We have
previously reported an insulin independence rate of 79% at 1 year (2), ...
Cited by 2 - Related articles - All 4 versions

Diabetes Mellitus, Type


AN Hussain, MT Vincent - members.medscape.com
Diabetes mellitus (DM) is a multisystem disease with both biochemical and
anatomical consequences. It is a chronic disease of carbohydrate, fat, and
protein metabolism caused by the lack of insulin. In type 1 diabetes, ...
Cited by 1 - Related articles - Cached - All 3 versions

VMAT2 quantitation by PET as a biomarker for β-cell mass in health and disease


M Freeby, R Goland, M Ichise, A Maffei, R … - Diabetes, Obesity and Metabolism, 2008 - pt.wkhealth.com
Diabetes mellitus presents when there is inadequate insulin secretion to meet
the body's demands. Although T1DM and T2DM vary in their development, both
exhibit dysfunction in insulin secretion and loss of β-cell mass (BCM). ...
Cited by 2 - Related articles - All 3 versions

[CITATION] Pathogenesis of type 1 diabetes mellitus


G SUSCEPTIBILITY, DOFI DEFICIENCY
Related articles - All 2 versions

[CITATION] Last literature review for version 16.3: Wed Oct 01 00: 00: 00 GMT 2008| This topic last …


GS Eisenbarth, DK McCulloch, DM Nathan, …
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[PDF] ROUNDS


N RAZACK, D WHERRETT, L LEITER, G … - genetics - endocrinologyrounds.ca
Significant advances in understanding the pathogenesis of type 1 diabetes
mellitus (T1DM) have led to a multitude of opportunities for intervention.
Specifically, a more thor- ough understanding has evolved of the potential ...
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[CITATION] Last literature review version 17.1: Thu Jan 01 00: 00: 00 GMT 2009| This topic last …


G SUSCEPTIBILITY, DOFI DEFICIENCY
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