- ►cardiovascres.org F Bohm, J Pernow - Cardiovascular Research, 2007 - cardiovascres.org Endothelin (ET)-1 is a potent vasoconstrictor peptide originally isolated from
endothelial cells. Its production is stimulated in a variety of different cell
types under the influence of risk factors for cardiovascular disease and ... Cited by 22 - Related articles - All 4 versions
- ►physiology.org I Lekli, G Szabo, B Juhasz, S Das, M Das, E … - American Journal of Physiology- Heart and Circulatory …, 2008 - Am Physiological Soc The resveratrol-induced cardiac protection was studied in Zucker obese rats.
Rats were divided into five groups: group 1, lean control; group 2, obese
control (OC); group 3, obese rats treated orally with 5 mg·kg –1 ·day ... Cited by 15 - Related articles - BL Direct - All 3 versions
V van Harmelen, A Eriksson, G Åström, K … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Adipose tissue had a marked net release of ET-1 in vivo, which was
2.5-fold increased in obesity. In adipocytes treated with ET-1, the
antilipolytic effect of insulin was attenuated in visceral but not in ... Cited by 7 - Related articles - BL Direct - All 4 versions
MM Elgebaly, A Kelly, AK Harris, H Elewa, V … - Canadian Journal of Physiology and Pharmacology, 2008 - ingentaconnect.com Abstract: Insulin resistance involves decreased phosphorylation of insulin
receptor substrate (IRS) proteins and (or) Akt. In the vasculature, modulated
Akt phosphorylation may cause impaired vasorelaxation via decreased eNOS ... Cited by 5 - Related articles - All 6 versions
R Muniyappa, M Iantorno, MJ Quon - Endocrinology and metabolism clinics of North America, 2008 - pubmedcentral.nih.gov Endothelial dysfunction and insulin resistance are frequently co-morbid states.
Vasodilator actions of insulin are mediated by phosphatidylinositol 3-kinase
(PI3K)-dependent signaling pathways that stimulate production of nitric ... Cited by 5 - Related articles - All 15 versions
- ►ahajournals.org E Raichlin, A Prasad, V Mathew, B Kent, DR … - Hypertension, 2008 - Am Heart Assoc Endothelin plays an important role in the pathogenesis of atherosclerosis. The
aim of the study was to evaluate the safety and hemodynamic and metabolic
responses to 6 months treatment with atrasentan, the selective endothelin-A ... Cited by 5 - Related articles - All 7 versions
AA Lteif, AD Fulford, RV Considine, I Gelfand … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Endogenous endothelin action is augmented in human obesity and type 2 diabetes
and contributes to endothelial dysfunction and impairs insulin-mediated
vasodilation in humans. We hypothesized that insulin resistance-associated ... Cited by 2 - Related articles - All 3 versions
- ►bentham.org M Tesauro, M Iantorno, F Schinzari, C Cardillo - Current Hypertension Reviews, 2009 - ingentaconnect.com Abstract: Over the last ten years it has become clear that vascular actions of
insulin extend beyond its ability to increase skeletal muscle blood flow and
glucose uptake. In addition to its role in regulating glucose, protein, and ... Related articles - All 3 versions
C Jung, A Shemyakin, F Böhm, J Pernow - Diabetes and Metabolism, 2009 - Elsevier MPs are small membrane vesicles that are released from many different cell types
in response to a variety of conditions, including apoptosis, chemical stimuli
such as cytokines, endotoxins and proinflammatory factors, and physical ... Related articles - All 2 versions
N Yoon, AA Lteif, KA Han, KJ Mather - Journal of the American Society of Hypertension, 2008 - Elsevier Endothelin contributes to abnormalities in peripheral blood vessel function of
subjects with obesity, with or without concurrent type 2 diabetes mellitus, but
it is unknown if endothelin contributes specifically to obesity and ... Related articles - All 7 versions
