- ►diabetesjournals.org SE Kahn, B Zinman, JM Lachin, SM Haffner, … - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—In men, fracture rates did not differ between treatment groups. In
women, at least one fracture was reported with rosiglitazone in 60 patients
(9.3% of patients, 2.74 per 100 patient-years), metformin in 30 patients ... Cited by 37 - Related articles - BL Direct - All 19 versions
AV Schwartz, DE Sellmeyer - Expert Opin. Drug Saf., 2008 - informahealthcare.com Rosiglitazone and pioglitazone are associated with increased fracture risk in
women, and, for rosiglitazone, more rapid bone loss. Negative skeletal effects
of these thiazolidinediones (TZDs) have also been observed in animal and in ... Cited by 23 - Related articles - BL Direct - All 5 versions
M Monami, B Cresci, A Colombini, L Pala, D … - Diabetes Care, 2008 - Am Diabetes Assoc OBJECTIVE—Hypoglycemic treatments could modulate the risk for fractures in
many ways. Most studies have not explored the effect on the incidence of bone
fractures of individual oral hypoglycemic agents, rather all oral ... Cited by 17 - Related articles - BL Direct - All 8 versions
AV Schwartz, DE Sellmeyer - Current Osteoporosis Reports, 2007 - Springer Recent studies have added to the evidence that type 1 and type 2 diabetes are
associated with increased risk of hip fracture and other fractures. More
frequent falls probably account for some of this increased risk, but ... Cited by 8 - Related articles - All 2 versions
I Kanazawa, T Yamaguchi, M Yamamoto, M … - Calcified Tissue International, 2008 - Springer Abstract Although patients with type 2 diabetes show no bone mineral density
(BMD) reduction, fracture risks are known to increase. It is unclear why the
patients have an increased risk of fracture despite sufficient BMD. We ... Cited by 7 - Related articles - All 2 versions
I Kanazawa, T Yamaguchi, S Yano, M … - Biochemical and Biophysical Research …, 2008 - Elsevier It is unclear whether metformin, one of the anti-hyperglycemic agents commonly
used for type 2 diabetes, could affect bone formation through activation of
AMP-activated protein kinase (AMPK). In order to clarify this issue, we ... Cited by 4 - Related articles - All 2 versions
- ►nih.gov KW Lyles, AP Schenck, CS Colón-Emeric - Osteoporosis International, 2008 - Springer Abstract Summary Nursing home residents with a history of hip fractures or prior
osteoporotic fractures were found to have an increased risk of another
osteoporotic fracture over the ensuing two years when compared to nursing ... Cited by 4 - Related articles - All 5 versions
Y Kawashima, JC Fritton, S Yakar, S Epstein, … - Bone, 2009 - Elsevier Type 2 diabetics often demonstrate normal or increased bone mineral density, yet
are at increased risk for bone fracture. Furthermore, the anti-diabetic oral
thiazolidinediones (PPARγ agonists) have recently been shown to increase ... Cited by 3 - Related articles - All 26 versions
S Epstein, D LeRoith - Bone, 2008 - Elsevier Diabetes and osteoporosis are both diseases of epidemic proportions whose
incidence is increasing worldwide. The etiology of osteoporosis is
multifactorial and may differ for type 1(T1DM) as compared to type 2 ... Cited by 4 - Related articles - All 23 versions
- ►diabetesjournals.org HF Chen, CA Ho, CY Li - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—The overall incidences of hip fracture for diabetic men and women,
respectively, were 3.01 and 6.75/1,000 person-years, which were higher than
those for control men and women. There were significant interactions of ... Cited by 2 - Related articles - BL Direct - All 5 versions