- ►endojournals.org L Aguilar-Bryan, J Bryan - Endocrine Reviews, 2008 - Endocrine Soc An explosion of work over the last decade has produced insight into the multiple
hereditary causes of a nonimmunological form of diabetes diagnosed most
frequently within the first 6 months of life. These studies are providing ... Cited by 15 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org MI McCarthy, AT Hattersley - Diabetes, 2008 - Am Diabetes Assoc Genetic factors for many decades have been known to play a critical role in the
etiology of diabetes, but it has been only recently that the specific genes have
been identified. The identification of the underlying molecular genetics ... Cited by 9 - Related articles - All 4 versions
J Støy, SAW Greeley, VP Paz, H Ye, AN … - Pediatric diabetes, 2008 - pubmedcentral.nih.gov Mutations in KCNJ11, ABCC8, or INS are the cause of permanent neonatal diabetes
mellitus in about 50% of patients diagnosed with diabetes before 6 months of age
and in a small fraction of those diagnosed between 6 and 12 months. The aim ... Cited by 5 - Related articles - All 4 versions
SE Flanagan, S Clauin, C Bellanné-Chantelot, … - Hum Mutat, 2009 - interscience.wiley.com The beta-cell ATP-sensitive potassium (K ATP ) channel is a key component of
stimulus-secretion coupling in the pancreatic beta-cell. The channel couples
metabolism to membrane electrical events bringing about insulin secretion. ... Cited by 5 - Related articles - All 3 versions
MA Pacanowski, CW Hopley, CL Aquilante - Expert Opin. Drug Metab. Toxicol., 2008 - informahealthcare.com Background: Numerous effective oral pharmacologic therapies are available to
treat type 2 diabetes. However, a substantial number of patients do not achieve
the expected glucose-lowering response, or may be predisposed to adverse ... Cited by 2 - Related articles - BL Direct - All 6 versions
JM Locke, LW Harries, 2008 - pubmedcentral.nih.gov In the eukaryotic cell a number of molecular mechanisms exist to regulate the
nature and quantity of transcripts intended for translation. For monogenic
diabetes an understanding of these processes is aiding scientists and ... Cited by 1 - Related articles - All 3 versions
EJ Pearl, CK Bilogan, S Mukhi, DD Brown, ME … - Dev Dyn, 2009 - interscience.wiley.com Understanding how the pancreas develops is vital to finding new treatments for a
range of pancreatic diseases, including diabetes and pancreatic cancer. Xenopus
is a relatively new model organism for the elucidation of pancreas ... Cited by 1 - Related articles - All 2 versions
DF Steiner, SY Park, J Støy, LH Philipson, GI … - Diabetes, Obesity and Metabolism, 2009 - interscience.wiley.com The preeminent role of the beta cell is to manufacture, store and release
insulin. The mature insulin molecule is composed of two polypeptide chains
designated as A and B that are joined by two pairs of disulfide bonds with ... Related articles - All 3 versions
