I Pagel-Langenickel, J Bao, L Pang, MN Sack - Endocrine Reviews, 2009 - Endocrine Soc Multiple organs contribute to the development of peripheral insulin resistance, with the major
contributors being skeletal muscle, liver, and adipose tissue. Because insulin resistance usually
precedes the development of type 2 diabetes mellitus (T2DM) by many years, ...
SFE Praet, LJC van Loon - Acta Diabetologica - Springer Abstract Structured exercise is considered an important cornerstone to achieve good glycemic
control and improve cardiovascular risk profile in Type 2 diabetes. Current clinical guidelines
acknowledge the therapeutic strength of exercise intervention. This paper reviews the ... Related articles - All 4 versions
JF Dumas, G Simard, M Flamment, PH Ducluzeau, P … - Diabetes and Metabolism, 2009 - Elsevier The precise cause of insulin resistance and type 2 diabetes is unknown. However, there is a
strong association between insulin resistance and lipid accumulation — and, in particular, lipotoxic
fatty acid metabolites — in insulin-target tissues. Such accumulation is known to cause ... Related articles - All 2 versions