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Implications of amylin receptor agonism: integrated neurohormonal mechanisms and …


JD Roth, H Maier, S Chen, BL Roland - Archives of Neurology, 2009 - Am Med Assoc
Amylin receptor agonism is emerging as part of an integrated neurohormonal
therapeutic approach for managing diabetes mellitus (DM) and body weight.
Pramlintide acetate, an analogue of the pancreatic hormone amylin, has been ...
Cited by 2 - Related articles - All 3 versions

It Takes Two to Tango: Combined Amylin/Leptin Agonism as a Potential Approach to …


JL Chan, JD Roth, C Weyer - Journal of Investigative Medicine, 2009 - journals.lww.com
Abstract: The discovery of leptin in 1994 was a seminal event in obesity
research. It helped to establish that body weight is tightly reg- ulated by a
complex neurohormonal feedback system and that obesity should be viewed as ...
Related articles

Targeting the Incretin System in Type 2 Diabetes Mellitus


M Potenza, EJ Rayfield - Mount Sinai Journal of Medicine: A Journal of …, 2009 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
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degraded, the site should continue to be functional. We recommend using the ...
Related articles - All 2 versions

Obesity treatment: novel peripheral targets


BCT Field, OB Chaudhri, SR Bloom - British Journal of Clinical Pharmacology, 2009 - interscience.wiley.com
Our knowledge of the complex mechanisms underlying energy homeostasis has
expanded enormously in recent years. Food intake and body weight are tightly
regulated by the hypothalamus, brainstem and reward circuits, on the basis ...
Related articles

What are the risks and the benefits of current and emerging weight-loss medications?


JR Robinson, KD Niswender - Current Diabetes Reports, 2009 - Springer
Obesity is epidemic; new medications and therapeutic options are urgently needed
to reduce the assoc iated health care burden. The initial clinical strategy for
weight loss is lifestyle modification involving a combination of diet, ...
Related articles - All 2 versions

[PDF] X OBESITY


JQ Purnell - 74.205.62.209
Obesity and its associated disorders are leading causes of morbidity and
premature mortality around the world. Obese persons are also vulnerable to low
self-esteem and depres- sion because of the psychological and social ...
Related articles

Gut peptides: targets for antiobesity drug development?


TH Moran, MJ Dailey - Endocrinology, 2009 - Endocrine Soc
Gut peptides play multiple roles in the controls of gastrointestinal function
and in the initiation and termination of meals. Plasma levels of these peptides
are differentially affected by the presence of nutrients in the digestive ...
Related articles - All 2 versions


 


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