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Recent clinical trials in diabetes–implications for managing older patients


GC Hawthorne, AJ Yarnall - Reviews in Clinical Gerontology, 2009 - Cambridge Univ Press
Summary The prevalence of type 2 diabetes is set to increase, and with it the complications associated
with diabetes. Since 2007 there have been a number of significant trials that may change the
way we think about treating people with diabetes, especially our older patients. These ...
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Regulation of intracerebral arteriolar tone by Kv channels: effects of glucose and …


SV Straub, H Girouard, PE Doetsch, RM … - American Journal of …, 2009 - Am Physiological Soc
Voltage-gated potassium (K v ) channels in vascular smooth muscle cells (VSMC) are critical
regulators of membrane potential and vascular tone. These channels exert a hyperpolarizing
influence to counteract the depolarizing effects of intraluminal pressure and ...
Related articles - All 3 versions

Cognitive function and risks of cardiovascular disease and hypoglycaemia in …


BE de Galan, S Zoungas, J Chalmers, C Anderson, C … - Diabetologia, 2009 - Springer
Abstract Aims/hypothesis The relationship between cognitive function, cardiovascular disease
and premature death is not well established in patients with type 2 diabetes. We assessed the
effects of cognitive function in 11,140 patients with type 2 diabetes who participated in the ...
Related articles - All 2 versions

Exercise and cognitive function: a hypothesis for the association of type II diabetes …


GNO Brito - Diabetology and Metabolic Syndrome, 2009 - pubmedcentral.nih.gov
The association of type II diabetes mellitus (DM2) with Alzheimer's disease (AD) has received
considerable attention in recent years. In the present paper, a hypothesis for this association
from an evolutionary perspective, with emphasis on the close interplay between exercise ...
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Neuronal IGF-1 resistance reduces A {beta} accumulation and protects against …


S Freude, MM Hettich, C Schumann, O Stohr, L Koch, C … - The FASEB Journal, 2009 - FASEB
Alzheimer's disease (AD) is characterized by progressive neurodegeneration leading to loss
of cognitive abilities and ultimately to death. Postmortem investigations revealed decreased expression
of cerebral insulin-like growth factor (IGF)-1 receptor (IGF-1R) and insulin receptor ...
Cited by 2 - Related articles - All 3 versions


 


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