M Kipnes - Expert Opinion on Investigational Drugs, 2009 - informahealthcare.com The global incidence of type 2 diabetes mellitus is increasing. Hyperglycemia
contributes to both the complications associated with diabetes mellitus and
progression of the underlying disease. New agents that lower blood glucose ... Cited by 1 - Related articles - All 6 versions
S Nair, JPH Wilding - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc Context: Sodium-glucose cotransporter 2 (SGLT2) expressed in the proximal renal
tubules accounts for about 90% of the reabsorption of glucose from tubular
fluid. Genetic defects of SGLT2 result in a benign familial renal ...
VC Woo - Expert Opin. Pharmacother., 2009 - informahealthcare.com Diabetes incidence continues to increase dramatically and is associated with
serious microvascular and macrovascular complications. People with type 2
diabetes form a heterogeneous group; treatment regimens and therapeutic ... Related articles - All 3 versions
A Statements - medscape.com Laurie E. Scudder, MS, NP Accreditation Coordinator, Continuing Professional
Education Department, MedscapeCME; Clinical Assistant Professor, School of
Nursing and Allied Health, George Washington University, Washington, DC; ...
A Bo³dys, B Okopieñ - Pharmacological Reports, 2009 - rabbit.if-pan.krakow.pl Abstract: In the last few years, the type 2 sodium glucose co-transporters
(SGLT2) have been the subject of particular attention as a new, potent group of
anti-diabetic drugs. SGLT2 inhibitors block glucose reabsorption in the ... View as HTML
WN Washburn - Expert Opinion on Therapeutic Patents, 2009 - informahealthcare.com Background: A critical factor for maintenance of glucose balance is the renal
recovery of glucose from the glomerular filtrate mediated primarily by sodium
glucose co-transporter 2 (SGLT2). This capacity can be modulated by SGLT2 ... Related articles
R Santer, J Calado - Clinical Journal of the American Society of Nephrology, 2009 - Am Soc Nephrol Four members of two glucose transporter families, SGLT1, SGLT2, GLUT1, and
GLUT2, are differentially expressed in the kidney, and three of them have been
shown to be necessary for normal glucose resorption from the glomerular ...
A Statements - medscape.com Vivian A. Fonseca, MD, FRCP Vivian A. Fonseca, MD, Professor of Medicine and
Pharmacology and Tullis-Tulane Alumni Chair in Diabetes, Tulane University
Health Sciences Center, New Orleans, Louisiana (Transitioning to) Chief, ... Related articles - All 2 versions
LD GROSSMAN, L LEITER, A ADVANI, G … - endocrinologyrounds.ca Despite a plethora of therapeutic options for the treatment of type 2 diabetes
mellitus (T2DM), the ability to normalize glucose levels and reduce long-term
com- plications of diabetes with treatment remains elusive. From the ... Related articles - View as HTML
