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Scholar Results 1 - 4 of 4 citing Szendroedi: Impaired mitochondrial function and insulin resistance of skeletal muscle in.... (0.04 sec) 

Mitochondrial fitness and insulin sensitivity in humans


J Szendroedi, M Roden - Diabetologia, 2008 - Springer
Abstract Human mitochondria can be studied either in biopsies or by measuring
flux through ATP synthase and phosphocreatine recovery using magnetic resonance
spec- troscopy. Myocellular ATP production (flux through ATP synthase ...
Cited by 3 - Related articles - All 2 versions

Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction …


SM Hirabara, R Curi, P Maechler - Journal of Cellular Physiology, 2009 - interscience.wiley.com
Increased plasma levels of free fatty acids (FFA) occur in states of insulin
resistance such as obesity and type 2 diabetes mellitus. These high levels of
plasma FFA are proposed to play an important role for the development of ...
Related articles - All 2 versions

High Prevalence of Impaired Glucose Homeostasis and Myopathy in Asymptomatic and …


AL Frederiksen, TD Jeppesen, J Vissing, M … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc
Introduction: The point mutation of 3243A>G mtDNA is the most frequent cause of
mitochondrial diabetes, often presenting as the syndrome maternally inherited
diabetes and deafness (MIDD). The mutation may also cause myopathy, ataxia, ...
Related articles

The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance


I Pagel-Langenickel, J Bao, L Pang, MN Sack - Endocrine Reviews, 2009 - Endocrine Soc
Multiple organs contribute to the development of peripheral insulin resistance,
with the major contributors being skeletal muscle, liver, and adipose tissue.
Because insulin resistance usually precedes the development of type 2 ...


 


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