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Scholar Results 1 - 10 of about 41 citing Porcellati: Comparison of pharmacokinetics and dynamics of the long-acting insulin analogs.... (0.08 sec) 

A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine …

- nih.gov
J Rosenstock, M Davies, PD Home, J Larsen, … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis This 52-week multinational, randomised, open-label,
parallel-group, non-inferiority trial compared clinical outcomes following
supplementation of oral glu- cose-lowering drugs with basal insulin ...
Cited by 74 - Related articles - BL Direct - All 9 versions

Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with …


RG Bretzel, U Nuber, W Landgraf, DR Owens, … - The Lancet, 2008 - Elsevier
In the 44-week, parallel, open study that was undertaken in 69 study sites
across Europe and Australia, 418 patients with type 2 diabetes mellitus that was
inadequately controlled by oral hypoglycaemic agents were randomly assigned ...
Cited by 50 - Related articles - All 24 versions

Intention to treat--initiating insulin and the 4-T study

- leicestershirediabetes.org.uk [PDF] 
GT McMahon, RG Dluhy - The New England journal of medicine, 2007 - nejm.highwire.org
The question of how to initiate insulin therapy in patients with type 2 diabetes
has become increasingly complicated as the range of insulin formulations with
differing time–activity profiles has expanded. Clinicians seeking to ...
Cited by 19 - Related articles - BL Direct - All 11 versions

Similar progression of diabetic retinopathy with insulin glargine and neutral protamine …

- nih.gov
J Rosenstock, V Fonseca, JB McGill, M Riddle, … - Diabetologia, 2009 - Springer
Abstract Aims/hypothesis This long-term study was designed to further
characterise the retinal safety profile of insulin glargine and human neutral
protamine Hagedorn (NPH) insulin in patients with type 2 diabetes mellitus. ...
Cited by 15 - Related articles - All 10 versions

Prevention of Hypoglycemia While Achieving Good Glycemic Control in Type 1 Diabetes


P Rossetti, F Porcellati, GB Bolli, CG Fanelli - Diabetes Care, 2008 - Am Diabetes Assoc
Insulin therapy in diabetes, both at onset and after several years' duration, is
primarily directed to maintain near-normoglycemia to prevent the onset and/or
delay progression of long-term complications (1,2). However, it is ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Beyond the era of NPH insulin-long-acting insulin analogs: chemistry, comparative …


DR Owens, GB Bolli - Diabetes Technology & Therapeutics, 2008 - liebertonline.com
The new rDNA and DNA-derived “basal” insulin analogs, glargine and detemir,
represent significant ad- vancement in the treatment of diabetes compared with
conventional NPH insulin. This review describes blood glucose homeostasis ...
Cited by 7 - Related articles - All 3 versions

New insulin analogues and routes of delivery: pharmacodynamic and clinical considerations


P Roach - Clinical Pharmacokinetics, 2008 - ingentaconnect.com
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Cited by 6 - Related articles - All 5 versions

The interpretation of glucose clamp studies of long-acting insulin analogues: from …


SGHA Swinnen, F Holleman, JH DeVries - Diabetologia, 2008 - Springer
Abstract Glucose clamp studies assessing the time–action profile of
long-acting insulin analogues have reported conflicting results. In an attempt
to reconcile the data, we organised an expert meeting of four leading ...
Cited by 4 - Related articles - All 2 versions

The pharmacokinetic and pharmacodynamic properties of different formulations of biphasic …


T Heise, U Eckers, K Kanc, JN Nielsen, L … - Diabetes Technology & Therapeutics, 2008 - liebertonline.com
Background: Type 2 diabetes patients on premixed insulin are commonly prescribed
biphasic insulin with low prandial insulin content, such as biphasic insulin
aspart (BIAsp) 30, comprising 30% insulin aspart (IAsp). The new ...
Cited by 3 - Related articles - All 3 versions

The role of new basal insulin analogues in the initiation and optimisation of insulin therapy …


MA Baxter - Acta Diabetologica, 2008 - Springer
Abstract Intensive insulin therapy aimed at achieving normoglycaemia is becoming
increasingly accepted in the treatment of type 2 diabetes (T2DM) to reduce the
risk of diabetes-related complications. Insulin therapy is increas- ingly ...
Cited by 3 - Related articles - All 3 versions


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