ID Goldfine, GJ Smith - Proceedings of the National Academy of …, 1976 - National Acad Sciences ABSTRACT Specific binding sites for l25I4labeled insulin were detected in purified nucleiisolated
from rat liver. Binding was rapid, reversible, and directly proportional to the number of nuclei
employed. Unlabeled native insulin, at concentrations as low as 1 ng/ml, significantly ... Cited by 87 - Related articles - All 7 versions
- ►nih.gov [PDF] S Terris, DF Steiner - Journal of Clinical Investigation, 1976 - pubmedcentral.nih.gov A BSTRACT The retention and degradation of insu- lin by isolated perfused liver have been
examined. Noncyclically perfused livers from streptozotocin-dia- betic rats retained 25% and
degraded 10% of 'I-insulin administered as a 1-min pulse. On gel filtration (Sepha- dex ... Cited by 62 - Related articles - All 4 versions
- ►pnas.org [PDF] Y Shechter, KJ Chang, S Jacobs, P … - Proceedings of the …, 1979 - National Acad Sciences Page 1. Proc. Natl. Acad. Sci. USA Vol. 76, No. 6, pp. 2720-2724, June 1979 Biochemistry
Modulation of binding and bioactivity of insulin by anti-insulin antibody: Relation to
possible role of receptor self-aggregation in hormone action ... Cited by 53 - Related articles - All 7 versions
- ►nih.gov [PDF] J Jaspan, K Polonsky - Journal of Clinical Investigation, 1982 - pubmedcentral.nih.gov JONATHAN JASPAN and KENNETH POLONSKY, Department of Medicine, University of Chicago
and the Pritzker School of Medicine, Chicago, Illinois 60637 ... ABSTRA CT Oral glucose (25
g) fed to seven healthy, conscious dogs resulted in an increase in peripheral plasma ... Cited by 48 - Related articles - All 4 versions
[CITATION] The insulin receptor: properties and regulation
- ►nih.gov [PDF] K Kurokawa, FJ Silverblatt, KL Klein, MS … - Journal of Clinical …, 1979 - pubmedcentral.nih.gov ABSTRACT To investigate a possible action of insulin on the glomerulus, the binding 1251-insulin
to the isolated glomeruli prepared from rat kidney was examined. When incubated at 22°C,
'251-insulin binding proceeded with time and reached a steady state at 45 min at which ... Cited by 23 - Related articles - All 4 versions
- ►nih.gov [PDF] JM Olefsky, M Kobayashi - Journal of Clinical Investigation, 1978 - pubmedcentral.nih.gov AB S TRACT Fasting leads to an increase in the ability ofadipocytes to bind insulin, and this was
accounted for by an increase in the affinity ofthe receptors for insulin without any change in the
number of receptors per cell. Binding affinity can increase because of a decrease in the ... Cited by 17 - Related articles - All 5 versions
P Menuelle, C Plas - Diabetologia, 1981 - Springer Summary. Binding of 12~I-insulin and the stimulatory effect of insuhn on 14C-glucose incorporation
into glycogen have been studied in cultured fetal rat hepatocytes. Measurement of both variables
was possible at 37 ~ because of the slow rate of insulin degradation in the medium. 125I- ... Cited by 17 - Related articles - All 2 versions
MJ Carmena, MD Fernandez-Moreno, JC … - Cell Biochem …, 1986 - interscience.wiley.com Insulin receptors have been characterized in rat prostatic epithelial cells by using [ 125 I]insulin
and a variety of physicochemical conditions. The binding data at equilibrium (2h at 15°C) could
be interpreted in terms of two populations of insulin receptors: a class of receptors with ... Cited by 13 - Related articles - All 3 versions
