- ►nih.gov [PDF] RS Spielman, RE McGinnis, WJ Ewens - American Journal of Human Genetics, 1993 - pubmedcentral.nih.gov Page 1. Am. J. Hum. Genet. 52:506-516, 1993 Transmission Test for Linkage
Disequilibrium: The Insulin Gene Region and Insulin-dependent Diabetes Mellitus ( ... Cited by 2893 - Related articles - BL Direct - All 10 versions
JL Davies, Y Kawaguchi, ST Bennett, JB … - Nature, 1994 - cms1.daegu.ac.kr ARTICLES A genome-wide search for human type 1 diabetes susceptibility genes
June L. Davies, Yoshihiko Kawaguchi, Simon T. Bennett, James B. Copeman, Heather
J. Cornell, Lynn E. Pritchard, Peter W. Reed, Stephen CL Gough, Suzanne C. ... Cited by 1060 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org [PDF] A Bonnardeaux, E Davies, X Jeunemaitre, I … - Hypertension, 1994 - Am Heart Assoc Abstract We conducted the present study to determine whether the angiotensin II
type I receptor (AT,) gene might be implicated in human essential hypertension
by using case-control and linkage studies. The entire coding and 3' ... Cited by 618 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] RS Spielman, WJ Ewens - The American Journal of Human Genetics, 1998 - Elsevier Linkage analysis with genetic markers has been successful in the localization of
genes for many monogenic human diseases. In studies of complex diseases,
however, tests that rely on linkage disequilibrium (the simultaneous ... Cited by 533 - Related articles - BL Direct - All 13 versions
ST Bennett, AM Lucassen, SCL Gough, EE … - Nature Genetics, 1995 - nature.com The IDDM2 locus encoding susceptibility to type 1 diabetes was mapped previously
to a 4.1−kb region spanning the insulin gene and a minisatellite or variable
number of tandem repeats (VNTR) locus on human chromosome 11p15.5. By ... Cited by 530 - Related articles - All 3 versions
- ►oxfordjournals.org L Nistico, R Buzzetti, LE Pritchard, B Van … - Human Molecular Genetics, 1996 - Oxford Univ Press Susceptibility to autoimmune insulin-dependent (type 1) diabetes mellitus is
determined by a combination of environmental and genetic factors, which include
variation in MHC genes on chromosome 6p21 (IDDM1) and the insulin gene on ... Cited by 440 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] WJ Ewens, RS Spielman - American Journal of Human Genetics, 1995 - pubmedcentral.nih.gov Summary Disease association with a genetic marker is often taken as a
preliminary indication of linkage with disease sus- ceptibility. However,
population subdivision and ad- mixture may lead to disease association even ... Cited by 413 - Related articles - BL Direct - All 9 versions
- ►nih.gov [PDF] N Risch - American journal of human genetics, 1987 - pubmedcentral.nih.gov SUMMARY The relationship between increased risk in relatives over population
prevalence (XR = KRIK) and probability of sharing zero marker alleles identical
by descent (ibd) at a linked locus (such as HLA) by an affected relative ... Cited by 409 - Related articles - All 5 versions
BR Seizinger, RL Martuza, JF Gusella, 1986 - nature.com The application of recombinant DNA techniques has identified two fundamental
mechanisms of tumorigenesis in man. The first involves a qualitative or
quantitative change in an oncogene (see ref. 1 for review). In the second, ... Cited by 318 - Related articles - All 4 versions
