- ►joslinresearch.org [PDF] LJ Scott, KL Mohlke, LL Bonnycastle, CJ … - Science, 2007 - sciencemag.org 333 article(s) on the ISI Web of Science. cited by This article has been ... :
subject collections This article appears in the following ... 2007 by the
American Association for the Advancement of Science; all rights reserved. ... Cited by 773 - Related articles - BL Direct - All 12 versions
SFA Grant, G Thorleifsson, I Reynisdottir, R … - Nature Genetics, 2006 - nature.com NM_030756We have previously reported suggestive linkage of type 2 diabetes
mellitus to chromosome 10q 1 . We genotyped 228 microsatellite markers in
Icelandic individuals with type 2 diabetes and controls throughout a ... Cited by 651 - Related articles - BL Direct - All 11 versions
- ►thelancet.com BC Martin, JH Warram, AS Krolewski, JS … - The Lancet, 1992 - Elsevier Type 2 diabetes mellitus is characterised by resistance of peripheral tissues to
insulin and a relative deficiency of insulin secretion. To find out which is the
earliest or primary determinant of disease, we used a minimum model of ... Cited by 594 - Related articles - BL Direct - All 5 versions
P Froguel, H Zouali, N Vionnet, G Velho, M … - New England Journal of Medicine, 1993 - content.nejm.org Background and Methods Non-insulin-dependent diabetes mellitus (NIDDM) is a
genetically heterogeneous disorder. Maturity-onset diabetes of the young, a form
of NIDDM with an early age of onset and autosomal dominant inheritance, can ... Cited by 477 - Related articles - BL Direct - All 6 versions
JC Brüning, J Winnay, S Bonner-Weir, SI … - CELL-CAMBRIDGE MA-, 1997 - cell.com NIDDM is a polygenic disease characterized by insulin resistance in muscle, fat,
and liver, followed by a failure of pancreatic β cells to adequately compensate
for this resistance despite increased insulin secretion. Mice double ... Cited by 346 - Related articles - Cached - BL Direct - All 8 versions
PH Froguel, M Vaxillaire, F Sun, G Velho, H …, 1992 - nature.com NON-INSULIN-DEPENDENT diabetes mellitus (NIDDM) is a major health problem,
affecting 5% of the world population. Genetic factors are important in NIDDM,
but the mechanisms leading to glucose intolerance are unknown 1,2 . Genetic ... Cited by 307 - Related articles - All 6 versions
E Ferrannini - Endocrine Reviews, 1998 - Endocrine Soc 1. Clinically, NIDDM is diagnosed on the basis of raised plasma glucose levels
(no other substrate or hormone being considered) that can be controlled without
exogenous insulin (although proneness to ketosis may eventually appear) ... Cited by 309 - Related articles - BL Direct - All 7 versions
- ►gotoknow.org [PDF] J Kaprio, J Tuomilehto, M Koskenvuo, K … - Diabetologia, 1992 - Springer Summary. We studied the cumulative incidence, concord- ance rate and
heritability for diabetes mellitus in a nation- wide cohort of 13,888 Finnish
twin pairs of the same sex. The twins were born before 1958 and both ... Cited by 292 - Related articles - BL Direct - All 4 versions
- ►nih.gov S Wiltshire, AT Hattersley, GA Hitman, M … - The American Journal of Human Genetics, 2001 - Elsevier Improved molecular understanding of the pathogenesis of type 2 diabetes is
essential if current therapeutic and preventative options are to be extended. To
identify diabetes-susceptibility genes, we have completed a primary ... Cited by 250 - Related articles - BL Direct - All 14 versions
