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Scholar Results 1 - 10 of about 163 citing Sadelain: Prevention of type I diabetes in NOD mice by adjuvant immunotherapy.. (0.17 sec) 

The effect of infections on susceptibility to autoimmune and allergic diseases


JF Bach - New England journal of medicine, 2002 - content.nejm.org
Infectious agents can induce autoimmune diseases in several experimental settings, some of
which have clinical counterparts. A variety of mechanisms have been invoked to explain these
observations, including molecular mimicry and an increase in the immunogenicity of ...
Cited by 762 - Related articles - BL Direct - All 5 versions

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus


A Rabinovitch - Diabetes Metab Res Rev, 1998 - interscience.wiley.com
Correlation studies between cytokines expressed in islets and autoimmune diabetes development
in NOD mice and BB rats have demonstrated that -cell destructive insulitis is associated with
increased expression of proinflammatory cytokines (IL-1, TNF , and IFN ) and type 1 ...
Cited by 342 - Related articles - BL Direct - All 3 versions

Homeostatic expansion of T cells during immune insufficiency generates …

- tamu.edu [PDF] 
C King, A Ilic, K Koelsch, N Sarvetnick - Cell, 2004 - Elsevier
During illness and stress, the immune system can suffer a considerable loss of T cells
(lymphopenia). The remaining T cells undergo vigorous compensatory expansion, known as
homeostatic proliferation, to reconstitute the immune system. Interestingly, human ...
Cited by 295 - Related articles - All 14 versions

Insulin immunization of nonobese diabetic mice induces a protective insulitis …

- nih.gov [PDF] 
A Muir, A Peck, M Clare-Salzler, YH Song, … - Journal of Clinical …, 1995 - pubmedcentral.nih.gov
We reported previously that daily injections of isophane insulin prevented both hyperglycemia
and insulitis in non- obese diabetic (NOD) mice (Atkinson, M., N. Maclaren; and R. Luchetta.
1990. Diabetes. 39:933-937). The possible mechanisms responsible include reduced ...
Cited by 179 - Related articles - BL Direct - All 9 versions

Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer.

- nih.gov [PDF] 
MJ Clare-Salzler, J Brooks, A Chai, K Van … - Journal of Clinical …, 1992 - pubmedcentral.nih.gov
The purpose of this study was to determine the effect of den- dritic cell (DC) transfers on the incidence
of diabetes in female nonobese diabetic (NOD) mice. Groups of 4-wk-old NOD fe- male mice
were given a single foot pad of DCs (70-90% purity) isolated from the draining lymph ...
Cited by 152 - Related articles - All 7 versions

Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus …


A Cooke, P Tonks, FM Jones, H O'Shea, P … - Parasite …, 1999 - interscience.wiley.com
The spontaneous development of insulin dependent diabetes mellitus in non-obese diabetic
(NOD) mice has been shown to be mediated by a Th1 response against beta cell antigens. It
is known that in murine models of Schistosoma mansoni infection, egg production is ...
Cited by 117 - Related articles - BL Direct - All 6 versions

Induction of FOXP3-expressing regulatory CD4pos T cells by human mature …


V Verhasselt, O Vosters, C Beuneu, C … - European journal of …, 2004 - interscience.wiley.com
Current literature suggests that T cells recognizing antigen on mature dendritic cells (DC) differentiate
into effector T cells whereas tolerance is induced when antigen is presented by immature
DC. We investigated the consequences of the interactions between immature or ...
Cited by 104 - Related articles - BL Direct - All 3 versions

[PDF] Hematopoietic stem-cell defects underlying abnormal macrophage development …


DV Serreze, JW Gaedeke, EH … - Proceedings of the …, 1993 - National Acad Sciences
ABSTRACT The immunopathogenesis of autoimmune in- sulin-dependent diabetes in NOD
mice entails defects in the development of macrophages (M$s) from hematopoietic pre-
cursors. The present study analyzes the cellular and molecular basis underlying our ...
Cited by 94 - Related articles - BL Direct - All 8 versions

Islet recovery and reversal of murine type 1 diabetes in the absence of any infused …


J Nishio, JL Gaglia, SE Turvey, C Campbell, C Benoist, … - Science, 2006 - sciencemag.org
A list of selected additional articles on the Science Web sites ... 52 article(s) on the ISI Web of
Science. cited by This article has been ... : subject collections This article appears in the following
... 2006 by the American Association for the Advancement of Science; all rights reserved. ...
Cited by 87 - Related articles - BL Direct - All 7 versions

Early autoantibody responses in prediabetes are IgG1 dominated and suggest …

- jimmunol.org
E Bonifacio, M Scirpoli, K Kredel, M … - The Journal of …, 1999 - Am Assoc Immnol
The islet autoimmunity of preclinical type 1 diabetes remains poorly characterized in
humans. In this paper, the IgG subclass response to the islet autoantigens insulin, glutamic acid
decarboxylase, and IA-2 was studied sequentially from birth to diabetes onset or current ...
Cited by 79 - Related articles - BL Direct - All 3 versions


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