- ►shouxi.net KF Petersen, S Dufour, D Befroy, R Garcia, … - The New England journal of medicine, 2004 - nejm.highwire.org Methods We performed hyperinsulinemic–euglycemic clamp studies in combination
with infusions of [6,6- 2 H 2 ]glucose in healthy, young, lean,
insulin-resistant offspring of patients with type 2 diabetes and insulin- ... Cited by 781 - Related articles - BL Direct - All 14 versions
- ►upmc.fr [PDF] KF Petersen, D Befroy, S Dufour, J Dziura, C … - Science, 2003 - sciencemag.org 420 article(s) on the ISI Web of Science. cited by This article has been ... :
subject collections This article appears in the following ... 2003 by the
American Association for the Advancement of Science; all rights reserved. ... Cited by 695 - Related articles - All 14 versions
GC Farrell, CZ Larter - Hepatology, 2006 - gidiv.ucsf.edu Nonalcoholic steatohepatitis (NASH), the lynchpin between steatosis and
cirrhosis in the spectrum of nonalcoholic fatty liver disorders (NAFLD), was
barely recognized in 1981. NAFLD is now present in 17% to 33% of Americans, ... Cited by 387 - Related articles - View as HTML - BL Direct - All 4 versions
- ►jbc.org VT Samuel, ZX Liu, X Qu, BD Elder, S Bilz, D … - Journal of Biological Chemistry, 2004 - ASBMB Short term high fat feeding in rats results specifically in hepatic fat
accumulation and provides a model of non-alcoholic fatty liver disease in which
to study the mechanism of hepatic insulin resistance. Short term fat ... Cited by 339 - Related articles - BL Direct - All 6 versions
C Schmitz-Peiffer, DL Craig, TJ Biden - Journal of Biological Chemistry, 1999 - ASBMB We have employed C2C12 myotubes to investigate lipid inhibition of
insulin-stimulated signal transduction and glucose metabolism. Cells were
preincubated for 18 h in the absence or presence of free fatty acids (FFAs) ... Cited by 287 - Related articles - BL Direct - All 5 versions
LH Storlien, LA Baur, AD Kriketos, DA Pan, … - Diabetologia, 1996 - Springer The history of research into the relationship between dietary fat intake and
impaired insulin action has its origin in the work of Himsworth approximately 60
years ago [1, 2]. In a series of pioneering studies using crude indices of ... Cited by 246 - Related articles - BL Direct - All 4 versions
R Kaaks - Cancer causes and control, 1996 - Springer Breast cancer incidence rates are high in societies with a Western lifestyle
characterized by low levels of physical activity, and by an energy-dense diet
rich in total and saturated fat and refined carbohydrates. Epidemiologic ... Cited by 219 - Related articles - BL Direct - All 6 versions
- ►nih.gov K Morino, KF Petersen, S Dufour, D Befroy, J … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig To further explore the nature of the mitochondrial dysfunction and insulin
resistance that occur in the muscle of young, lean, normoglycemic,
insulin-resistant offspring of parents with type 2 diabetes (IR offspring), ... Cited by 165 - Related articles - BL Direct - All 10 versions
- ►physiology.org BA Ellis, A Poynten, AJ Lowy, SM Furler, DJ … - American Journal of Physiology- Endocrinology And …, 2000 - Am Physiological Soc Long-chain acyl-CoAs (LCACoA) are an activated lipid species that are key
metabolites in lipid metabolism; they also have a role in the regulation of
other cellular processes. However, few studies have linked LCACoA content ... Cited by 149 - Related articles - BL Direct - All 4 versions
JA Marshall, DH Bessesen, RF Hamman - Diabetologia, 1997 - Springer Hyperinsulinaemia, a marker for insulin resistance, has been associated with
significant adverse out- comes. Hyperinsulinaemia is frequently associated with
hypertension, hyperlipidaemia and coronary heart disease [1], and ... Cited by 140 - Related articles - BL Direct - All 4 versions
