JW Yoon, CS Yoon, HW Lim, QQ Huang, Y Kang, KH … - Science, 1999 - sciencemag.org NIM) Triton X-100 was added to 900 l of sperm suspension in NIM [see (12)] and mixed by trituration
for 30 s on ice. Cells were pelleted by centrifugation for 1 min at 20,000g, 2°C and thoroughly
resuspended in 2 ml of ice-cold NIM before repelleting for 2 min at 20,000g, 2°C. We ... Cited by 197 - Related articles - BL Direct - All 8 versions
DR Wegmann, M Norbury-Glaser, D … - European journal of …, 1994 - interscience.wiley.com Numerous investigations have demonstrated that T cells are involved in destruction of cells in
the NOD mouse, a widely studied model of type I diabetes. In this report we describe a series
of islet-specific T cell lines established from islet-infiltrating lymphocytes obtained from ... Cited by 187 - Related articles - BL Direct - All 3 versions
B Wang, A Gonzalez, C Benoist, D Mathis - Eur J Immunol, 1996 - interscience.wiley.com While it is generally accepted that T cells are critical for the development of diabetes in the
non-obese diabetic (NOD) mouse, the precise functions of the CD4 + and CD8 + subsets remain
ill-defined. Transfer experiments have provided evidence that CD4 + cells are the disease ... Cited by 149 - Related articles - BL Direct - All 3 versions
- ►rupress.org D Schmidt, J Verdaguer, N Averill, P … - Journal of Experimental …, 1997 - jem.rupress.org Certain major histocompatibility complex (MHC) class II haplotypes encode elements providing
either susceptibility or dominant resistance to the development of spontaneous autoimmune
diseases via mechanisms that remain undefined. Here we show that a pancreatic beta ... Cited by 148 - Related articles - BL Direct - All 5 versions
J Katz, C Benoist, D Mathis - European journal of immunology, 1993 - interscience.wiley.com An early step in the development of autoimmune diabetes is lymphocyte infiltration into the islets
of Langerhans of the pancreas, or insulitis. The infiltrate contains both CD4 + and CD8 + T cells
and both are required for progression to diabetes in non-obese diabetic (NOD) mice. It ... Cited by 138 - Related articles - BL Direct - All 3 versions
- ►rupress.org HS Jun, CS Yoon, L Zbytnuik, N van Rooijen, … - Journal of Experimental …, 1999 - jem.rupress.org We have shown previously that the inactivation of macrophages in nonobese diabetic (NOD)
mice results in the prevention of diabetes; however, the mechanisms involved remain
unknown. In this study, we found that T cells in a macrophage-depleted environment lost ... Cited by 139 - Related articles - BL Direct - All 6 versions
- ►nih.gov V Viglietta, SC Kent, T Orban, DA … - Journal of Clinical …, 2002 - Am Soc Clin Investig Insulin-dependent type 1 diabetes is an autoimmune disease mediated by T lymphocytes recognizing
pancreatic islet cell antigens. Glutamic acid decarboxylase 65 (GAD65) appears to be an important
autoantigen in the disease. However, T cells from both patients with type 1 diabetes and ... Cited by 101 - Related articles - BL Direct - All 10 versions
V Panoutsakopoulou, ME Sanchirico, KM Huster, M … - Immunity, 2001 - Elsevier The clinical association between viral infection and onset or exacerbation of autoimmune disorders
remains poorly understood. Here, we examine the relative roles of molecular mimicry and nonspecific
inflammatory stimuli in progression from infection to autoimmune disease. Murine herpes ... Cited by 87 - Related articles - BL Direct - All 7 versions
JW Yoon, HS Jun - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2001 - cms1.daegu.ac.kr ABSTRACT: Insulin-dependent diabetes mellitus (IDDM), also known as type 1 diabetes, is an
organ-specific autoimmune disease resulting from the destruc- tion of insulin-producing pancreatic
ß cells. The hypothesis that IDDM is an autoimmune disease has been considerably ... Cited by 73 - Related articles - View as HTML - BL Direct - All 5 versions
