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Scholar Results 1 - 10 of about 160 citing Cryer: Banting Lecture. Hypoglycemia: the limiting factor in the management of IDDM.. (0.08 sec) 

Less hypoglycemia with insulin glargine in intensive insulin therapy for type 1 …

- diabetesjournals.org [PDF] 
RE Ratner, IB Hirsch, JL Neifing, SK Garg, TE … - Diabetes care, 2000 - Am Diabetes Assoc
The Diabetes Control and Complica- tions Trial (DCCT) (1) and other stud- ies (2,3) provide conclusive
evidence that maintaining tight glycemic control can prevent or delay microvascular
complica- tions in individuals with type 1 diabetes. Attempts to achieve glycemic control ...
Cited by 347 - Related articles - BL Direct - All 8 versions

Autonomic regulation of islet hormone secretion–implications for health and …


B Ahren - Diabetologia, 2000 - Springer
Our knowledge of autonomic regulation of islet func- tion begins with the observation by Paul
Langerhans that pale, non-myelinated nerve fibres exist in the rabbit and cat pancreas. These
nerve fibres were shown tube connected to intrapancreatic ganglia and form a rich neural ...
Cited by 250 - Related articles - BL Direct - All 7 versions

Hypoglycaemia: The limiting factor in the glycaemic management of Type I and …


P Cryer - Diabetologia, 2002 - Springer
Hypoglycaemia is the limiting factor in the glycaemic management of diabetes. Iatrogenic hypoglycaemia
is typically the result of the interplay of insulin excess and compromised glucose counterregulation
in Type I (insulin-dependent) diabetes mellitus. Insulin concen- trations do not decrease ...
Cited by 225 - Related articles - BL Direct - All 6 versions

Hypoglycemia is the limiting factor in the management of diabetes


PE Cryer - Diabetes/Metabolism Reviews - interscience.wiley.com
Hypoglycemia is the limiting factor, both conceptually and in practice, in the management of diabetes
mellitus. While the long-term goal of diabetes research must remain the cure and the prevention
of the disease and reasonable near-term goals might include perfect insulin replacement ...
Cited by 112 - Related articles - BL Direct - All 3 versions

Amylin replacement with pramlintide as an adjunct to insulin therapy improves long …


RE Ratner, R Dickey, M Fineman, DG Maggs, … - Diabetic …, 2004 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 111 - Related articles - BL Direct - All 5 versions

β-Cell function and the development of diabetes-related complications in the …

- diabetesjournals.org
MW Steffes, S Sibley, M Jackson, W Thomas - Diabetes Care, 2003 - Am Diabetes Assoc
In patients with type 1 diabetes, measurement of connecting peptide (C-peptide), cosecreted
with insulin from the islets of Langerhans, permits estimation of remaining β-cell secretion of
insulin. In this retrospective analysis to distinguish the incremental benefits of residual ...
Cited by 113 - Related articles - BL Direct - All 5 versions

Autonomic mediation of glucagon secretion during hypoglycemia: implications for …

- diabetesjournals.org [PDF] 
GJ Taborsky, B Ahren, PJ Havel - Diabetes, 1998 - Am Diabetes Assoc
This article examines the role of the autonomic nervous system in mediating the increase of glucagon
secretion observed during insulin-induced hypoglycemia (IIH). In the first section, we briefly review
the importance of the -cell response in recovery from hypoglycemia under both ...
Cited by 103 - Related articles - BL Direct - All 5 versions

Effect of hypoglycemia on brain glycogen metabolism in vivo


IY Choi, ER Seaquist, R Gruetter - Journal of neuroscience …, 2003 - pubmedcentral.nih.gov
Cited by 69 - Related articles - BL Direct - All 4 versions

Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia …


S Banarer, VP McGregor, PE Cryer - Diabetes, 2002 - Am Diabetes Assoc
Because absence of the glucagon response to falling plasma glucose concentrations plays a
key role in the pathogenesis of iatrogenic hypoglycemia in patients with insulin-deficient diabetes
and the mechanism of this defect is unknown, and given evidence in experimental ...
Cited by 67 - Related articles - BL Direct - All 7 versions

Glucose transport in brain and retina: implications in the management and …


AK Kumagai, JD Foundation - Diabetes Metab Rev, 1999 - interscience.wiley.com
Neural tissue is entirely dependent on glucose for normal metabolic activity. Since glucose stores
in the brain and retina are negligible compared to glucose demand, metabolism in these tissues
is dependent upon adequate glucose delivery from the systemic circulation. In the brain, ...
Cited by 62 - Related articles - BL Direct - All 6 versions


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