D Le Roith - The New England journal of medicine, 1997 - nejm.highwire.org The three peptide hormones, or growth factors, in the IGF family — insulin,
IGF-I, and IGF-II — have approximately 50 percent of their amino acids in
common. Insulin is synthesized in the beta cells of the pancreas as ... Cited by 425 - Related articles - BL Direct - All 18 versions
K Mori, A Yoshimoto, K Takaya, K Hosoda, H … - FEBS letters, 2000 - Elsevier Ghrelin is a novel growth hormone-releasing peptide with a unique acylated
structure. Here we reveal that prepro-ghrelin gene is expressed in the mouse
kidney and glomerulus. We also show by reverse-phase high performance ... Cited by 205 - Related articles - All 4 versions
- ►ahajournals.org A Cittadini, H Stromer, SE Katz, R Clark, AC … - Circulation, 1996 - Am Heart Assoc From the Charles A. Dana Research Institute and the Harvard-Thorndike
Laboratory, Department of Medicine (Cardiovascular Division [AC, HS, SEK, JPM,
PSD] and Endocrinology [ACM]), Beth Israel Hospital and Harvard Medical ... Cited by 205 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org P Delafontaine, YH Song, Y Li - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc The vascular insulin-like growth factor (IGF)-1 system includes the IGFs, the
IGF-1 receptor (IGF-1R), and multiple binding proteins. This growth factor
system exerts multiple physiologic effects on the vasculature through both ... Cited by 140 - Related articles - BL Direct - All 9 versions
- ►endojournals.org DR Clemmons, AC Moses, MJ McKay, A … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc Insulin-like growth factor-I (IGF-I) enhances insulin action in normal subjects
and in patients with both type 1 and 2 diabetes; however, its administration is
associated with significant side effects in a high percentage of patients. ... Cited by 131 - Related articles - BL Direct - All 5 versions
S Feld, R Hirschberg - Endocrine reviews, 1996 - Endocrine Soc I. Introduction: GROWTH hormone and the insulin-like growth factors (IGFs)
compile a complex, interrelated system of three peptide hormones, GH, IGF-I, and
IGF-II, their specific receptors, and a series of binding proteins. The ... Cited by 132 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] G Di Cola, MH Cool, D Accili - Journal of Clinical Investigation, 1997 - pubmedcentral.nih.gov We have investigated the metabolic actions of recombinant human IGF-1 in mice
genetically deficient of insulin recep- tors (IR ). After intraperitoneal
administration, IGF-1 caused a prompt and sustained decrease of plasma ... Cited by 95 - Related articles - BL Direct - All 9 versions
CL Acerini, CM Patton, MO Savage, A Kernell … - The Lancet, 1997 - Elsevier With a dose of 40 μg/kg rhlGF-l daily, we found significant reductions in HbA
1c compared with placebo (p=O.O3), without changes in body-mass index, rate of
hypoglycaemia, insulin dose, or circulating concentrations of IGF-binding ... Cited by 78 - Related articles - BL Direct - All 9 versions
- ►endojournals.org MY Donath, G Sutsch, XW Yan, B Piva, HP … - Journal of Clinical Endocrinology & Metabolism, 1998 - Endocrine Soc Insulin-like growth factor I (IGF-I) enhances myofibrillar development in
cardiomyocytes of rats in culture and in vivo. In addition, IGF-I has
vasodilatory effects and improves cardiac function in healthy volunteers. ... Cited by 77 - Related articles - BL Direct - All 4 versions
- ►endojournals.org S Boonen, C Rosen, R Bouillon, A Sommer, M … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc The administration of recombinant human IGF-I complexed with its predominant
binding protein IGF binding protein-3 (rhIGF-I/IGFBP-3) may allow the safe
administration of higher doses of IGF-I than can be accomplished with ... Cited by 68 - Related articles - BL Direct - All 8 versions
